BACKGROUND Despite several studies investigating the pathophysiologic effects of tourniquet usage in extremity surgeries, there are not enough data about these effects in adhesion release surgeries of burn patients. In the light of numerous metabolic changes of burn tissues, we tried to determine whether there are any significant differences in metabolic responses of burn tissues to tourniquet...

BACKGROUND To select optimal candidates for extrapleural pneumonectomy (EPP), we retrospectively evaluated the usefulness of metabolic response by fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) after neoadjuvant chemotherapy to predict prognosis for patients with resectable malignant pleural mesothelioma (MPM) who underwent EPP in a multicenter study. PATIENT...

Gamma aminobutyrate (GABA) is a non-protein amino acid that is thought to play an important role in the modulation of the central response to stress. Mechanisms by which GABA may facilitate these responses to stress are metabolic and/or mechanical disruptions. Environmental stresses increase GABA accumulation through cytosolic acidification, induce an acidic pH-dependent activation of glutamate...

Peritoneal lymphomatosis is an extremely rare presentation of lymphoma. Due to its relative low frequency, it receives much less attention than peritoneal carcinomatosis. The challenge is to differentiate between lymphomatosis and carcinomatosis, as well as peritoneal tuberculosis or other pathologic entities within the peritoneal cavity based essentially on radiologic features. 18</...

conclusions the rvr is the strongest factor of svr and infection with hcv genotype 2 is significantly associated with rvr. neither biochemical and/or metabolic factors seem to exert influence on rvr. objectives the main aim of this study was to assess the strength of rvr, as a predictive factor of antiviral treatment response. patients and methods using univariate and multivariate analysis, we ...

Marine natural products are a source of promising agents for cancer treatment. However, there is a need to improve the evaluation of their mechanism of action in tumors. Metabolomics of the response to anti-tumor agents is a tool to reveal candidate biomarkers and metabolic targets. We used two-dimensional high-resolution magic angle spinning proton-NMR spectroscopy-based metabolomics to invest...

objective: we aimed to evaluate association between thyroid dysfunction, and lipid profile and glycated hemoglobin in type 2 diabetic patients. materials and methods: this cross-sectional study was carried out in type 2 diabetic patients who referred to yazd diabetes research center. a total of 1200 type 2 diabetic patients who had thyroid dysfunction according to clinical examinations and labo...

Short-term oxygen consumption and filtration rate experiments were conducted to evaluate the response of edible cockle Cerastoderma edule when infested by the Digenean trematod Labratrema minimus. In this experiment the metabolic activities of bivalves were measured to detennine this particular aspect of the host-parasite interaction. We have used the Bucephalidae digenea Labratrema minimus inf...

Metabolic flexibility is the capacity for the organism to adapt fuel oxidation to fuel availability. The inability to modify fuel oxidation in response to changes in nutrient availability has been implicated in the accumulation of intramyocellular lipid and insulin resistance. The metabolic flexibility assessed by the ability to switch from fat to carbohydrate oxidation is usually impaired duri...