نتایج جستجو برای: merkel cell carcinoma

تعداد نتایج: 1881734  

Journal: :Current oncology reports 2011
Shailender Bhatia Olga Afanasiev Paul Nghiem

Merkel cell carcinoma (MCC) is an aggressive skin malignancy with a high mortality rate and an increasing incidence. The recent discovery of Merkel cell polyomavirus has revolutionized our understanding of MCC pathogenesis. Viral oncoproteins appear to play a critical role in tumor progression and are expressed in the majority of MCC tumors. Virus-specific humoral and cellular immune responses ...

Journal: :Head & neck 2017
Tobin Strom Arash O Naghavi Jane L Messina Sungjune Kim Javier F Torres-Roca Jeffery Russell Vernon K Sondak Tapan A Padhya Andy M Trotti Jimmy J Caudell Louis B Harrison

BACKGROUND We hypothesized that radiotherapy (RT) would improve both local and regional control with Merkel cell carcinoma of the head and neck. METHODS A single-institution institutional review board-approved study was performed including 113 patients with nonmetastatic Merkel cell carcinoma of the head and neck. Postoperative RT was delivered to the primary tumor bed (71.7% cases) ± drainin...

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