To establish that a stable, long-lasting form of memory exists in Drosophila, we trained third-instar larvae by electroshocking them in the presence of a specific odor using a Pavlovian conditioning procedure. We show that conditioned odor avoidance produced in larvae still was present in adults 8 d later. Such memory through metamorphosis was specific to the temporal pairing of odor and shock;...

Memory consolidation studies, including those examining the role of the basolateral amygdala (BLA), have traditionally used techniques limited in their temporal and spatial precision. The development of optogenetics provides increased precision in the control of neuronal activity that can be used to address the temporal nature of the modulation of memory consolidation. The present experiments, ...

Recent studies have proposed that a common mechanism may underlie spatial attention and spatial working memory. One proposal is that spatial working memory is maintained by attention-based rehearsal [Awh, E., Jonides, J., & Reuter-Lorenz, P. A. (1998). Rehearsal in spatial working memory. Journal of Experimental Psychology: Human Perception and Performance, 24(3), 780-790], and so a spatial att...

Episodic memory is reconceived as a memory system that retains highly detailed sensory perceptual knowledge of recent experience over retention intervals measured in minutes and hours. Episodic knowledge has yet to be integrated with the autobiographical memory knowledge base and so takes as its context or referent the immediate past of the experiencing self (or the 'I'). When recalled it can b...

College undergraduates were asked to record events from their lives, and then to date those events. Data were collected from groups of subjects using a set of cue words to prompt the events, from individual subjects, for individual cue words, from groups of subjects using no cue words, and from subjects who kept diaries. If it is assumed that the subjects encoded an equal number of events from ...

Taking a memory test not only assesses what one knows, but also enhances later retention, a phenomenon known as the testing effect. We studied this effect with educationally relevant materials and investigated whether testing facilitates learning only because tests offer an opportunity to restudy material. In two experiments, students studied prose passages and took one or three immediate free-...

Memory systems should be plastic to allow for learning; however, they should also retain earlier memories. Here we explore how synaptic weights and memories are retained in models of single neurons and networks equipped with spike-timing-dependent plasticity. We show that for single neuron models, the precise learning rule has a strong effect on the memory retention time. In particular, a soft-...

Animal models of amnesia have yielded many insights into the neural substrates of different types of memories. Some very important aspects of memory, however, have been ignored in research using experimental animals. For example, to examine long-term memory investigators traditionally have relied on measures of information acquisition, which stand in contrast to the measures of retention common...

The positive impact of sleep on memory consolidation has been shown for human subjects in numerous studies, but there is still sparse knowledge on this topic in rats, one of the most prominent model species in neuroscience research. Here, we examined the role of sleep in the object-place recognition task, a task closely comparable to tasks typically applied for testing human declarative memory:...

Previous studies have suggested that face memory is unique; however, evidence is inconclusive. To further explore this issue, we investigated recognition memory for unfamiliar faces and scenes. Participants (n = 123) intentionally memorized the stimuli and then engaged in recognition tests. Recognition was measured following short (20 minutes) and long (3 weeks) retention intervals. Encoding st...