Progressive headache consequent to drug overuse is an old critical issue. 1 Migraine specially and the development of its daily or near-daily presentation due to overuse of immediate-relief medications is suggested since the eighties when Mathew and col. described this transformation and named it transformed migraine. 2 These authors called the attention for the fact that migraine may progressi...

After the introduction of chronic migraine and medication overuse headache as diagnostic entities in The International Classification of Headache Disorders, Second Edition, ICHD-2, it has been shown that very few patients fit into the diagnostic criteria for chronic migraine (CM). The system of being able to use CM and the medication overuse headache (MOH) diagnosis only after discontinuation o...