Sjögren’s Syndrome (SS) is a chronic autoimmune disease characterized by exocrinopathy, with xerophthalmia and xerostomia. Patients SS may exhibit extra-glandular features such as neurologic symptoms. Peripheral neuropathy the most common neurological complication of primary (pSS). We report case 71-year-old female pSS admitted to Internal Medicine ward due sensorimotor symptoms petechiae. From...

The application of X-rays and ionising radiations for diagnostic radiology requires that the procedure is justified and optimised and that the exposure to the patient is kept as low as possible, without compromising image information. X-ray mammography is considered to be the most sensitive technique currently available for early detection of breast cancer. The magnitude of the absorbed radiati...

We report the case of glandular tularemia that developed in a man supposedly infected by a tick bite in Western Switzerland. Francisella tularensis (F. tularensis) was identified. In Europe tularemia most commonly manifests itself as ulcero-glandular or glandular disease; the diagnosis of tularemia may be delayed in glandular form where skin or mucous lesion is absent, particularly in areas whi...

AIMS To assess the role of human papillomavirus in the pathogenesis of adenocarcinoma in situ, endocervical glandular dysplasia (a presumed precursor of adenocarcinoma) and endocervical glandular epithelial giant cell change. METHODS Viral detection was carried out using an in situ hybridisation technique on paraffin wax sections. Biotinylated probes for human papillomavirus types 6/11, 16/18...

Recent studies have described premalignant changes in the endocervical epithelium, but morphological criteria for the diagnosis of cervical glandular atypia of lesser severity than adenocarcinoma in situ have not been established. Adenocarcinoma in situ is often associated with cervical intraepithelial neoplasia (CIN). The endocervical mucosa in 105 cases of CIN grade III was evaluated and comp...

Aromatase cytochrome P450 (P450arom) is an enzyme that catalyzes the conversion of androgen to estrogen. Expression of P450arom in extra-gonadal sites and locally-synthesized estrogen play an important role in physiological conditions. The purpose of this study was to investigate the cellular immunolocalization of androgen receptor (AR), P450arom, estrogen receptor alpha (ERa) and estrogen rece...

Glandular trichomes play important roles in protecting plants from biotic attack by producing defensive compounds. We investigated the metabolic profiles and transcriptomes to characterize the differences between different glandular trichome types in several domesticated and wild Solanum species: Solanum lycopersicum (glandular trichome types 1, 6, and 7), Solanum habrochaites (types 1, 4, and ...

Trichomes are widely distributed on surfaces of different organs in the grape genus Vitis and are of taxonomic utility. To explore the morphology, structure and ontogeny of Vitis trichomes, we investigated the diversity and distribution of trichomes in 34 species of Vitis. Two main types of trichomes in Vitis are documented: non-glandular and glandular. Within non-glandular trichomes, ribbon an...

Organ dose is the absorbed radiation energy from ionizing radiation to an organ, divided by the organ mass. Organ doses of a patient cannot be measured directly in the patient, but their determination requires dose measurements in anthropomorphic patient models i.e. phantoms or Monte Carlo simulations. Monte Carlo simulations can be performed for example by using computational phantoms or patie...