background: thalassemia is one of the most common hereditary disorders and beta-thalassemia major is its severe form. the present study is concerned with the analysis of liver function, thyroid function and estimation of critical serum ions as well as hematological characteristics in beta-thalassemia patients and controls. subjects and methods: the study included 54 patients with beta-thalassem...

OBJECTIVE To study the correlation between third-trimester serum ferritin concentration and hemoglobin and red cell indices to select the best hematologic characteristic to identify women who need iron therapy. METHODS In a prospective study, blood was drawn from pregnant women with hemoglobin above 10 g/dL, and thalassemia trait excluded at booking, at 28-30 weeks' gestation to study the cor...

Sodium (Na+) and potassium (K+) transport by the furosemide-sensitive Na+-K+ transport system, the Na+-K+ pump, and the cation leak(s) were studied in erythrocytes from DOC-water, DOC-salt, two-kidney, one clip (Sprague-Dawley), and spontaneously hypertensive rats (Wistar-Kyoto). Rubidium (Rb+) was used as a tracer for K+. After 4 weeks of DOC-salt hypertension, inward K+ (Rb+) transport by the...

Elevation of K-Cl cotransport in patients with homozygous hemoglobin (Hb) S or HbC increases red cell mean corpuscular hemoglobin concentration (MCHC) and contributes significantly to pathology. Elucidation of the origin of elevated K-Cl cotransport in red cells with mutant hemoglobins has been confounded by the concomitant presence of reticulocytes with high K-Cl cotransport. In red cells of c...

Background: Anemia is the most common complication due to CKD. Normocytic normochromic type of anemia in CKD is, but there also some microcytic hypochromic. Clinical examination such as erythrocyte indices and monitoring serum ferritin levels can help diagnose The purpose this study determine correlation between patients hemodialysis unit PKU Hospital Bantul.Methods: This research involved 50 a...

Objective: The thyroid gland has a very important role in hematopoiesis. Blood disorders are frequently seen patients with dysfunction and anemia is more common them. Thyroid hormones directly affect blood parameters by stimulating erythrocyte precursors indirectly enhancing erythropoietin production. present study was conducted to evaluate the effect of hypothyroidism on different hematologica...

INTRODUCTION Iron deficiency anemia is the leading cause of anemia worldwide. It may also be the leading cause of anemia in pregnancy, although this has not yet been demonstrated in our country. The aim of the study was to describe hematologic features of Cameroonian anemic pregnant women. METHODS This cross sectional analytical study was carried out in the maternity of the Yaoundé University...

Experiments were performed to explore whether adhesion differences among different density sickle (SS) cells are mainly caused by deformability characteristics attendant to density variations, which could affect their surface contacts with the endothelium, or caused by any changes in their membrane surface (eg, receptors). Also, what is the contribution of morphologic attributes of SS cells in ...

Elevation of K-Cl cotransport in patients with homozygous hemoglobin (Hb) S or HbC increases red cell mean corpuscular hemoglobin concentration (MCHC) and contributes significantly to pathology. Elucidation of the origin of elevated K-Cl cotransport in red cells with mutant hemoglobins has been confounded by the concomitant presence of reticulocytes with high K-Cl cotransport. In red cells of c...