نتایج جستجو برای: mcc
تعداد نتایج: 3226 فیلتر نتایج به سال:
Symbolic-reasoning systems, or rule-based expert systems, are used successfully in a wide variety of applications, from process control and credit evaluation to insurance underwriting and medical diagnosis. Still, some problems have proven impervious to solutions with purely symbolic techniques. In many of these areas, the methods that underlie artificial neural networks, or connectionist syste...
Recent developments in the realm of state estimation of stochastic dynamic systems in the presence of non-Gaussian noise have induced a new methodology called the maximum correntropy filtering. The filters designed under the maximum correntropy criterion (MCC) utilize a similarity measure (or correntropy) between two random variables as a cost function. They are shown to improve the estimators’...
Asplenic individuals are known to be at increased risk of infection with encapsulated bacteria. Recent United Kingdom recommendations stated that this at-risk group should receive one dose of the meningococcal serogroup C conjugate (MCC) vaccine. However, the immune response of asplenic individuals to MCC vaccine is unknown. The immune response of asplenics (n = 130) to immunization with the MC...
We discuss selected model checking techniques used in the tool TAPAAL for the reachability analysis of weighted Petri nets with inhibitor arcs. We focus on techniques that had the most significant effect at the 2015 Model Checking Contest (MCC). While the techniques are mostly well known, our contribution lies in their adaptation to the MCC reachability queries, their efficient implementation a...
Possible sources of excitatory synaptic input to the serotonergic metacerebral cell (MCC) were determined by stimulating various neurons in the cerebral ganglion. Firing of the previously identified histaminergic neuron C2 was found to produce synaptic input to the MCC. The synaptic input consists of fast excitatory-inhibitory synaptic potentials on a background of a slow EPSP. The slow EPSP ap...
PURPOSE Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor, often metastatic at presentation, for which current chemotherapeutic regimens are largely ineffective. As its pathogenesis is still unknown, we hypothesized that deregulation of signaling pathways commonly activated in cancer may contribute to MCC tumorigenesis and may provide insights into targeted therapy app...
Koljonen et al described an association between chronic lymphocytic leukemia (CLL) and Merkel cell polyomavirus (MCV)– positive Merkel cell carcinoma (MCC) in a recent large populationbased survey from Finland.1 CLL has been reported as a tumor significantly associated with MCC, validating the general findings of this study.2,3 This association suggests the possibility that MCV may play a role ...
1. We examined the effect of chronic (21 days) oral treatment with the thiazolidinedione, MCC-555 ((+)-5-[[6-(2-fluorbenzyl)-oxy-2-naphy]methyl]-2,4-thiazo lid inedione) on metabolic status and insulin sensitivity in obese (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats which display an impaired glucose tolerance (IGT) or overt diabetic symptoms, respectively. 2. MCC-555 treatment to o...
Merkel cell polyomavirus (MCPyV) has recently been identified in Merkel cell carcinoma (MCC), an aggressive cancer that occurs in sun-exposed skin. Conventional technologies, such as polymerase chain reaction (PCR) and immunohistochemistry, have produced conflicting results for MCPyV infections in non-MCC tumors. Therefore, we performed quantitative analyses of the MCPyV copy number in various ...
BACKGROUND Airway mucociliary clearance (MCC) is an important defense mechanism against pulmonary infections and is compromised in cystic fibrosis (CF). Cl- and HCO3- epithelial transport are integral to MCC. During pulmonary infections prostaglandin E2 (PGE2) production is abundant. AIM To determine the effect of PGE2 on airway Cl- and HCO3- secretion and MCC in normal and CF airways. METH...
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