BACKGROUND Within the animal kingdom, horses are among the most powerful aerobic athletic mammals. Determination of muscle respiratory capacity and control improves our knowledge of mitochondrial physiology in horses and high aerobic performance in general. METHODOLOGY/PRINCIPAL FINDINGS We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to ...

The maximum activities of 6-phosphofructokinase and oxoglutarate dehydrogenase in muscle provide quantitative indices of the maximum capacities of anaerobic g lycolys is and the Krebs cyc le ( i .e . the aerobic capacity) respectively. These activities were measured in red, whit% and cardiac muscle of bird~ and the rat. The a c t i v i t i e s in the white pectoral muscle of the domes t i c fow...

BACKGROUND AND OBJECTIVE Peak aerobic capacity (VO2 peak) is an important outcome measure in cystic fibrosis (CF), but measurement is not widely available and can be influenced by patient motivation, pain and fatigue. Alternative markers of disease severity would be helpful. Neural respiratory drive, measured using parasternal intercostal muscle electromyography (EMGpara), reflects the load to ...

Aerobic exercise capacity is decreased at altitude because of combined decreases in arterial oxygenation and in cardiac output. Hypoxic pulmonary vasoconstriction could limit cardiac output in hypoxia. We tested the hypothesis that acetazolamide could improve exercise capacity at altitude by an increased arterial oxygenation and an inhibition of hypoxic pulmonary vasoconstriction. Resting and e...

background: to establish a balance between work (physical exercise) and human, the aerobic capacity (vo2max) could be used as a measure. assessing heart rate in association to physiological symptoms is the most commonly used tools for the assessment of fatigue during physical exercise. this study aimed to investigate the association between the aerobic capacity and the heart rate of workers fro...

OBJECTIVE To investigate the effect of self exercise in cardiac rehabilitation on cardiopulmonary exercise capacity for selected patients with coronary artery disease. METHOD The subjects of this study were patients who received percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery and who participated in a cardiac rehabilitation program. The supervised exerc...

STUDY OBJECTIVE To determine the effect of an aerobic conditioning program on fitness, respiratory physiology, and resting lung function in patients with mild asthma. DESIGN Prospective cohort study. SETTING Outpatient rehabilitation facility. METHODS Five patients with mild intermittent asthma and five normal control subjects completed a 10-week aerobic conditioning program. Pulmonary fu...

Measurements of aerobic scope [the difference between minimum and maximum oxygen consumption rate ( and , respectively)] are increasing in prevalence as a tool to address questions relating to fish ecology and the effects of climate change. However, there are underlying issues regarding the array of methods used to measure aerobic scope across studies and species. In an attempt to enhance quali...

Hypoxia at high altitudes is often assumed to constrain exercise capacity, but there have been few high- versus low-altitude comparisons of species native to a wide range of altitudes. Such studies are ecologically realistic, as wild-caught animals tested at their native altitude are presumably maximally acclimated (via phenotypic plasticity) or adapted (by evolutionary change) to that altitude...