objective(s): previous studies have shown that thyroid hormones are necessary for normal development of many organs and because of the importance of skin as the largest and the most important organ in human body protection in spite of external environment, the study of thyroid hormones effects on skin development is considerable. in this survey we have tried to study the effects of maternal hyp...

OBJECTIVE It is unknown whether elevated maternal low-density lipoprotein cholesterol (LDL-C) levels lead to dyslipidemia in the offspring. Because this could have important consequences for cardiovascular prevention in mother and child, we explored the relationship between maternal familial hypercholesterolemia (FH) and lipids in adult offspring. METHODS AND RESULTS In a large cohort of both...

The placental metabolism can adapt to the environment throughout pregnancy to both the demands of the fetus and the signals from the mother. Such adaption processes include epigenetic mechanisms, which alter gene expression and may influence the offspring's health. These mechanisms are linked to the diversity of prenatal environmental exposures, including maternal under- or overnutrition or ges...

BACKGROUND Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offspring to chronic kidney disease (CKD). We aimed to determine whether the nuclear Farnesoid X receptor (FXR), known to play a role in maintaining homeostasis of glucose and lipid ...

this study was carried out to evaluate the effects of different dietary protein (30, 35, 40%) and lipid levels (10, 12, 14%) on growth performance and physiological changes of juveniles caspian kutum (rutilus frisii kutum). six hundred and seventy five fish (1.15 ± 0.01 g) were distributed into 27 aquaria (45 l) and were fed four times daily for 8 weeks. interaction between protein and lipid di...

Spontaneous preterm delivery (SPTD) with gestational age between 28 and 37 complete weeks was reported to have a genetic predisposition in lipids metabolism. This study aimed to investigate the association between the lipid levels and gene polymorphisms of ABCA1 (rs2422493), APOE (rs7412) and HMGCR (rs12916) in Chinese pregnant women with SPTD. A case-control study was conducted at the baseline...

background: a close relationship has been reported between level of serum iron and ischemic heart diseases which is either brought about through direct effect of serum iron on myocardial cells or as an indirect result of elevated serum lipid profile. a widespread use of iron supplements has been observed due to the high prevalence of iron deficiency anemia. yet an elevated serum lipid is strong...

In fish, the lipid resources of female form a link between environment and progeny, contributing to contents egg yolk. Variation environmental conditions is therefore expected affect quality via maternal pathways, reflecting female’s response factors before spawning. We investigated content lipids thyroid hormones in ovary eggs Baltic herring during 1988–2019, when salinity Sea first declined t...

Physiological pregnancy is associated with an increase in lipids from the first to the third trimester. This is a highly regulated response to satisfy energy and membrane demands of the developing fetus. Pregnancy disorders, such as pre-eclampsia, are associated with a dysregulation of lipid metabolism manifesting in increased maternal plasma lipid levels. In fetal placental tissue, only scarce...