In biological applications, the tandem mass spectrometry is a widely used method for determining protein and peptide sequences from an ”in vitro” sample. The sequences are not determined directly, but they must be interpreted from the mass spectra, which is the output of the mass spectrometer. This work is focused on a similarity-search approach to mass spectra interpretation, where the paramet...

In high-throughput proteomics the development of computational methods and novel experimental strategies often rely on each other. In certain areas, mass spectrometry methods for data acquisition are ahead of computational methods to interpret the resulting tandem mass spectra. Particularly, although there are numerous situations in which a mixture tandem mass spectrum can contain fragment ions...

The fragmentation mechanisms of monolignols under various energetic processes are studied with jet-cooled thermal desorption molecular beam (TDMB) mass spectrometry (MS), 25 keV Bi(3)(+) secondary ion MS (SIMS), synchrotron vacuum-ultraviolet secondary neutral MS (VUV-SNMS) and theoretical methods. Experimental and calculated appearance energies of fragments observed in TDMB MS indicate that th...

A laboratory study was carried out to investigate the single particle soil dust using aerosol time-of-flight mass spectrometry. The presence of crustal elements is observed in the mass spectra of individual particles. Potassium and iron constitute the two most commonly detected cations. Other common cations observed in the mass spectra of soil particles include sodium and magnesium. According t...

Despite a recent surge of interest in database-independent peptide identifications, accurate de novo peptide sequencing remains an elusive goal. While the recently introduced spectral network approach resulted in accurate peptide sequencing in low-complexity samples, its success depends on the chance of presence of spectra from overlapping peptides. On the other hand, while multistage mass spec...

Previous dilepton measurements in heavy-ion collisions have mainly focused on invariant mass spectra to clarify in-medium changes of vector meson properties. However, a dimuon is characterized by two scales — invariant mass M and transverse momentum pT . Like transverse momentum spectra of hadrons, pT spectra of dileptons arise from an interplay between emission temperature and collective trans...