Electrophoretic properties of chromatin subunits--nucleosomes--obtained by treatment of chromatin with the Serratia marcescens endonuclease have been studied. Double-stranded breaks of DNA between adjacent nucleosomes do not necessarily lead to their disjunction. Fragmentation of the DNA within the nucleosomes may proceed simultaneously with the breakdown of the DNA between the nucleosomes at e...

Most organisms reproduce through outcrossing, even though it comes with substantial costs. The Red Queen hypothesis proposes that selection from coevolving pathogens facilitates the persistence of outcrossing despite these costs. We used experimental coevolution to test the Red Queen hypothesis and found that coevolution with a bacterial pathogen (Serratia marcescens) resulted in significantly ...

Resting-cell suspensions of Serratia marcescens were able to convert, quantitatively, 0.3% vanillin to vanillic acid. The vanillic acid-producing activity reached a maximum after 28 h of incubation with 0.01% vanillin as an inducer.

BACKGROUND Cerebral abscesses are extremely rare in neonates. Serratia marcescens is an unusual cause of sepsis and neurological spread is especially ominous. PURPOSE To report the case of a 34-week neonate who developed this rare condition and to discuss diagnostic and therapeutic measures. CASE REPORT A 34-week male neonate sequentially developed respiratory distress syndrome, early sepsi...

BACKGROUND AND OBJECTIVE To describe the clinical features and treatment outcomes of 10 patients with culture-proven Serratia marcescens endophthalmitis. PATIENTS AND METHODS Records from the microbiology laboratory for the period from January 1980 through June 1993 were reviewed. Ten patients were identified who had positive anterior chamber or vitreous cultures and clinical signs of endopht...

Serratia marcescens has long been recognized as an important opportunistic pathogen, but the underlying pathogenesis mechanism is not completely clear. Here, we report a key pathogenesis pathway in S. marcescens comprising the RssAB two-component system and its downstream elements, FlhDC and the dominant virulence factor hemolysin ShlBA. Expression of shlBA is under the positive control of FlhD...

The production of a precipitate by Serratia marcescens on Oxoid MacConkey agar has proven useful as a laboratory diagnostic test. This phenomenon is specific for Serratia within the Enterobacteriaceae, although precipitate production is also given by Acinetobacter anitratus and some Pseudomonas, Alcaligenes, and Aeromonas species. Precipitate production seems to be specific for certain batches ...

The genus Serratia is one of the poorly studied among enterobacteria, which explains interest in these microorganisms and bacteriophages active towards microorganisms. aim this work was to study antigenic properties isolated by us from lysogenic cultures serrations environmental objects. investigated 16 phages against bacteria marcescens, various sources.