Purpose: Smear scores and induration sizes resulting from the PPD (tuberculin purified protein derivative) test can serve as indicators of whether a patient suffering from tuberculosis shows smear conversion or not. Methods: Using microbiological methods smear and sputum tests, patients diagnosed as infected with Mycobacterium tuberculosis between 2002 and 2015 were included in this study. All ...

This study was conducted to determine the frequency of infected children cohabiting with sputum-positive and negative tuberculous adults for grounding authenticity Montoux test in diagnosing tuberculosis among these groups. It inferred from that a significant figure positive tuberculin skin not found be diseased those results were diagnosed based on chest X-ray, sputum examination, FNAC enlarge...

According to experts, 2 billion people in the world are infected with causative agent of tuberculosis. A priority task diagnosis tuberculosis infection is use accurate, accessible and scalable tools. The tuberculin skin test (TST), or Mantoux test, interferon gamma release assay (IGRA) currently used diagnose infection. In 2022, World Health Organization (WHO) identified a fundamentally new cla...

BACKGROUND The QuantiFERON-TB-Gold Test (QFT) is more specific than the Mantoux skin-test to discriminate between Mycobacterium tuberculosis (MTB) and non-tuberculous mycobacterial (NTM) infections. Here we study the performance of the QFT in patients with NTM disease. METHODS From 2005 to 2011, nationwide patient data on positive NTM cultures (n = 925) were combined with nationwide data on Q...

OBJECTIVE To define optic neuritis associated with chikungunya virus (CHIKV) infection in a clinical setting. METHODS This observational case series includes 14 patients with clinical features of CHIKV infection and associated optic neuritis. Complete ophthalmic evaluations were performed, as well as other examinations, including Mantoux test, Widal test, blood profile, color vision, neuroima...

BACKGROUND Tuberculosis has again emerged as a growing public health concern in the United States. Among the homeless population, increased risk factors contribute to immunodeficiency, which can cause false-negative results on purified protein derivative (tuberculin) (PPD) skin testing, the standard screening procedure for tuberculosis in individuals. We evaluated the accuracy of PPD skin test ...

INTRODUCTION In Tuscany, Tuberculosis incidence is more than triplicate from 1982 to the beginning of the third millennium. The impact of this trend on open population is not known, as updated studies on Tuberculosis prevalence are not available. Tuberculin skin test provides the currently most widely used tool for assessing Tuberculosis transmission in a community and the prevalence of infecti...

BACKGROUND The purified protein derivative (PPD) skin test is the only widely used method which detects latent tuberculosis infection (LTBI) and is dependent on a normal T cell function. In rheumatoid arthritis (RA) the T cell function is altered, which may result in an inability to develop an adequate PPD reaction. OBJECTIVES To evaluate the response to PPD in patients with RA and to compare...