نتایج جستجو برای: mannose resistant
تعداد نتایج: 202850 فیلتر نتایج به سال:
In the current work, aromatic amines and alkyl halides have been converted to corresponding azides 2a‒d 4a-d by reaction with sodium nitrite azide respectively for halides. Then, dipropargyl ether derivative of D-mannose 8 has synthesized from diacetone mannose that obtained treatment (5) dry acetone in presence sulfuric acid. aldol condensation used prepare diol 7 diacetonide 6. The compound p...
Tunicamycin, an antibiotic which specifically inhibits the dolichol-mediated synthesis of glycoproteins, significantly decreased the incorporation of tritiated o-mannose and o-glucosamine into L1210 ascites leukemia cell glycoproteins at concentrations which affected the biosynthesis of proteins minimally. Mice re ceiving inoculations of LI 210 cells pretreated with 10 ^M tunicamycin in vitro s...
We have studied the posttranslational modifications of the 52-kD protein, an estrogen-regulated autocrine mitogen secreted by several human breast cancer cells in culture (Westley, B., and H. Rochefort, 1980, Cell, 20:353-362). The secreted 52-kD protein was found to be phosphorylated mostly (94%) on high-mannose N-linked oligosaccharide chains, and mannose-6-phosphate signals were identified. ...
Hygromycin A, an antibiotic produced by Streptomyces hygroscopicus, is an inhibitor of bacterial ribosomal peptidyl transferase. The antibiotic binds to the ribosome in a distinct but overlapping manner with other antibiotics and offers a different template for generation of new agents effective against multidrug-resistant pathogens. Reported herein are the results from a series of stable-isoto...
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