BACKGROUND The case fatality rate of severe malaria remains unacceptably high. N-acetylcysteine (NAC) is a safe compound that inhibits tumour necrosis factor (TNF) and impedes cytoadherence, both of which have been implicated in the pathogenesis of malaria complications. AIM To evaluate NAC as adjunctive therapy in severe malaria. DESIGN A placebo-controlled, double-blind prospective study,...

Aim: To determine the clinical course, therapy, complications and prognostic factors in patients with VKH disease. Design: Hospital-based retrospective study. Materials and methods: Medical records of all patients with VKH disease over an 11-year period were retrospectively analyzed. Statistical analysis used: SPSS, non-parametric method, Mann-Whitney test. Results: Twenty-three patients (38 ey...

The purpose of this study was to evaluate the electromyographic activity of the accessory inspiratory muscles and the diaphragmatic amplitude (DA) in nasal and mouth-breathing adults. The study evaluated 38 mouth-breathing (MB group) and 38 nasal-breathing (NB group) adults, from 18 to 30years old and both sexes. Surface electromyography (sEMG) was used to evaluate the amplitude and symmetry (P...

The purpose of this study was to define histological features determining the malignant potential of EGFR-mutated lung adenocarcinoma (LADC). Surgically resected tumors (EGFR-mutated LADCs with (21) and without (79) lymph node metastasis and EGFR wild-type LADCs with (26) and without (108) lymph node metastasis) and biopsy samples from inoperably advanced tumors (EGFR-mutated LADCs (78) and EGF...

PURPOSE To analyse prognostic features on quality of life (QoL) following radical cystectomy and urinary diversion via orthotopic neobladder in a single-centre patient cohort. MATERIALS AND METHODS Postoperative QoL of 152 patients was assessed retrospectively using the validated QLQ-C30 questionnaire. Potential associations of patient's quality of life including pre-and intraoperative charac...

Methods Coronary artery bypass grafting (CABG) and surgical correction of ischemic mitral valve were performed in 52 patients with coronary artery disease (CAD) and IMR and 52 patients with CAD and IMR underwent only CABG. In both groups they had moderate or severe mitral insufficiency. Serial transthoracic and transesophageal echocardiograms were performed before surgery, after 6 months and af...

Playing games for a long period can induce negative effect on the hands, especially median nerve. This study aims to compare nerve conduction between gamers and non-gamers. was analyzed with cross-sectional method of 40 subjects at University Mataram Hospital from September October 2020. The included non-gamers as controls. All groups were tested velocity using Electromyoneurography. Demographi...

Background: In the CT assessment of the carotid plaque, the analysis of the attenuation value is a fundamental parameter in order to classify the type of the tissue that composes the plaque. The purpose of this paper is to assess the intra-plaque attenuation variability in order to verify the potential reproducibility of HU measurements. Methods: In this retrospective study, 68 consecutive pati...