Pigmentation has become an important phenotypical characteristic, in the pharmaceutical, medicinal as well as in the cosmetic field. Plants and their extracts are inexpensive and rich resources of active compounds that can be utilized to inhibit tyrosinase activity as well as melanin production. Natural and synthetic chemical agents can frequently modulate the metabolism of pigmentation produce...

The gravity of the impact of renal failure on human health is well known and as there is no specific pharmacotherapy for renal failure, the current study was undertaken to evaluate the effect of root extract of Azima tetracantha, an ancient medicinal plant used in Siddha and Ayurvedhic systems of medicine. The experiment was done in glycerol-induced acute renal failure in Wistar albino rats. Th...

Rheum emodi or Himalayan rhubarb is a perennial herb belongs to family Polygonaceae. It has been used in various traditional systems as laxative, tonic, diuretic and to treat fever, cough, indigestion, menstrual disorder since antiquity. This paper consists of literature of Rheum emodi regarding its ethnobotany, folkloric uses, chemical properties and pharmacological studies. The material was c...

antioxidant activity of aerial part of cytisus scoparius, link (family leguminosae) was studied both by in vitro and in vivo models. different concentrations of different extracts of chloroform, ethyl acetate, methanol and hydroalcoholic extracts of plant were investigated for in vitro antioxidant activity using the thiocyanate method. the hydroalcoholic extract exhibited highest inhibitory act...

The aim of the study was to evaluate the nephroprotective and nephrocurative effects of Tephrosia purpurea (L.) Pers. leaves against gentamicin-induced acute renal injury in albino rats. The maximum free radical scavenging activity of the ethanolic extract was the basis for the selection of this extract for the in vivo study. Gentamicin (40 mg/kg, s.c.) was administered to induce toxicity in th...

Almécija and colleagues claim that we apply a simplified understanding of bone functional adaptation and that our results of human-like hand use in Australopithecus africanus are not novel. We argue that our results speak to actual behavior, rather than potential behaviors, and our functional interpretation is well supported by our methodological approach, comparative sample, and previous exper...

Our ongoing investigations on the stem bark of Mesua beccariana afforded a novel cyclodione coumarin, beccamarin, together with two known xanthones, mesuarianone, mesuasinone, two anthraquinones, 4-methoxy-1,3,5-trihydroxy-anthraquinone and 2,5-dihydroxy-1,3,4-trimethoxyanthraquinone and one coumarin, mammea A/AB. The structures were elucidated by 1D and 2D NMR and MS techniques.

The use of phytoconstituents single or combined with standard medicines has been utilized in cure different diseases. Many plants genus Cordia comprise trees and shrubs are widely distributed warmer regions have management various africana Lam. (family- Boraginaceae) is a small to medium-sized evergreen tree, 4 15 (30) m high, heavily branched spreading, umbrella-shaped rounded crown. Bole typi...

This work was performed to study the effect of allicin on hypertension and cardiac function in a rat model of CKD. The groups were control, CKD (5/6 nephrectomy), and CKD-allicin treated (CKDA) (40 mg/kg day/p.o.). Blood pressure was monitored (weekly/6 weeks). The cardiac function, vascular response to angiotensin II, oxidative stress, and heart morphometric parameters were determined. The CKD...