Background: Anthocyanins (ACNs) are the most prevalent flavonoids in berries and their health promoting effects on vascular functions are still discussed. The aim of the present study was to identify the antiinflammatory effect of ACNs on activated human umbilical vein endothelial cells (HUVECs) after their transport across an epithelial monolayer. Study design: We established a transwell epith...

Vineyards are characterized by their large spatial variability of solar irradiance (SI) and temperature, known to effectively modulate grape metabolism. To explore the role of sunlight in shaping fruit composition and cluster uniformity, we studied the spatial pattern of incoming irradiance, fruit temperature and metabolic profile within individual grape clusters under three levels of sunlight ...

Naturally occurring anthocyanins possess colorectal cancer chemopreventive properties in rodent models. We investigated whether mirtocyan, an anthocyanin-rich standardized bilberry extract, causes pharmacodynamic changes consistent with chemopreventive efficacy and generates measurable levels of anthocyanins in blood, urine, and target tissue. Twenty-five colorectal cancer patients scheduled to...

Consumption of fresh fruits and vegetables has been linked both anecdotally and clinically to the prevention or alleviation of chronic diseases and provides essential nourishment to mankind. The muscadine grape, a fruit indigenous to the southeastern U.S., contains several phenolic compounds that act as antioxidants and also other compounds, such as resveratrol, that can perform as a chemopreve...

Access this article online Quick Response Code: Website: www.phcogrev.com DOI: 10.4103/0973-7847.95854 INTRODUCTION Research on diabetes treatment is gaining ground as the world population with diabetes is rising each year, and is expected to hit 439 million adults by 2030.[1] The awareness on the issue has led to a vast discovery of new medications as well as natural products extracted from he...

Fruits are good sources of natural antioxidants such as carotenoids, vitamins, phenols, flavonoids, dietary glutathionine, and endogenous metabolites. These antioxidants are capable of performing a number of functions including acting as free radical scavengers, peroxide decomposers, singlet and triplet oxygen quenchers, enzyme inhibitors, and synergists. Active oxygen species are generated as ...

The present invention relates to plants of the genus Raphanus containing increased levels of anthocyanins. In particular the edible sprouts and turnips of the Raphanus plants contain high levels of anthocyanins and thereby provide health-promoting effects. The anthocyanins in the Raphanus plants are present at a level of at least 100 nmol per gram of fresh weight and have an absorbance maximum ...

The findings of clinical studies concerning the association between anthocyanins supplementation and blood pressure (BP) are inconsistent. In order to provide a more precise estimate of the overall effect of anthocyanins on systolic blood pressure (SBP) and diastolic blood pressure (DBP), we conducted a meta-analysis of clinical trials about anthocyanins supplementation and BP. PubMed, Web of S...