Exposure to asbestos can lead asbestosis or malignancy 10-40 years after initial exposure [1]. Although its use has been banned in multiple countries, past occupational leads most cases that we see present time. Malignant mesothelioma is an insidious and rare neoplasm arise from mesothelial surface cells, being Pleural Mesothelioma (MPM) the common type. Lifetime risk of developing among worker...

Descriptions of diffuse malignant mesothelioma date from the nineteenth century' but it was not until 1960 that Wagner et al2 described a series of cases of pleural mesothelioma from South Africa and linked them to crocidolite asbestos exposure. Malignant mesotheliomas may arise from the pleura, peritoneum, and pericardium and all may be associated with asbestos exposure. Malignant mesothelioma...

AIMS AND BACKGROUND During the 1990's, the traditional unimodal treatments (surgery, radiotherapy, chemotherapy, immunotherapy) for malignant pleural mesothelioma started to be combined in bimodal or multimodal strategies. However, recent population-based analyses of the survival of patients with malignant pleural mesothelioma indicate that even these treatments have not led to significant impr...

AIMS To examine the hypothesis that people with benign pleural disease or asbestosis have an increased risk of malignant mesothelioma beyond that attributable to their degree of asbestos exposure. METHODS Former workers and residents of the crocidolite mining and milling town of Wittenoom are participating in a cancer prevention programme (n = 1988). The first plain chest radiograph taken at ...

Pleural biopsies for the evaluation of malignant mesothelioma can be some of the most challenging cases faced by the practicing surgical pathologist. We review the epidemiology, clinical presentation, and imaging studies in patients with malignant mesothelioma, and then present a practical approach to the diagnosis using the cytologic features for malignancy and whether there is an epithelioid ...