background: momordica charantia (m. charantia) seed has been supposed to have an antifertility property but mechanisms underlying the infertility effect have not been investigated. objective: we investigated the antifertility effect of m. charantia ethanol seed extracts on reproductive toxicology and seminal and plasma testosterone in male wistar rats. materials and methods: the control group (...

Cyclophosphamide (CP) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. However, despite its wide spectrum of clinical uses, CP is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. Crataegus monogyna is one of the oldest medicinal plant has been shown to be cytoprotecti...

Nicotine (NIC) adversely influences male reproductive system. Achillea millefolium (Achm) as a medicinal plant is highly regarded for its antioxidant and anti-inflammatory properties. The present study was conducted to assess whether Achm inflorescences alcoholic extract could serve as a protective agent against reproductive toxicity in NIC-exposed male rats. Adult male rats were randomly divid...

Formaldehyde (FA), a ubiquitous environmental pollutant, has long been suspected of having male reproductive toxicity. However, FA male reproductive toxicity was inconclusive due to dearth of human studies. Therefore, we sought to investigate whether occupational exposure to FA affects semen quality. Semen quality including five conventional parameters and seven kinematics parameters were compa...

With fully conclusive findings about the toxicity of carbon nanotubes (CNTs) still up in the air, research on biomedical applications of CNTs is pushing full steam ahead. Adding to the list of potential concerns, a recent nanotoxicology study by a U.S.-Chinese research team looked into the impact of carbon nanotubes on male reproductive health. The translocation and biodistribution of nanoparti...

The study of reproductive toxicity includes measures of: female fertility and fecundability; other female reproductive effects, such as lowered age at menopause and menstrual disorders; and male reproductive effects, including altered sperm parameters, which may influence a couple’s fertility and/or fecundability. Very few studies prior to the 1997 review (Cal/EPA, 1997) or since have investiga...

introduction toxoplasma gondii is one of the most important pathogen that has adverse effect on reproductive function. evidence acquisition recent studies revealed that infection with t. gondii not only affect female reproduction, also cause male reproductive impairment. in clinical studies, high prevalence of toxoplasmosis in sterile men has been reported. in animal models, toxoplasmosis is as...