نتایج جستجو برای: malaria vectors
تعداد نتایج: 112085 فیلتر نتایج به سال:
Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the mosquito midgut and are widely considered to be an essential tool for malaria elimination. High-titer functional antibodies are required against target antigens to achieve effective transmission-blocking activity. We have fused Pfs25, the leading malaria TBV candidate antigen to IMX313, a molecular adju...
Malaria vaccine research has been ongoing since the 1980s with limited success. However, recent improvements in our understanding of the immune responses required to combat each stage of infection will allow for intelligent design of both antigens and their associated delivery vaccine vehicles/vectors. Synthetic carriers (also known as vectors) are usually particulate and have multiple properti...
The spread of resistance to pyrethroids in the major Afrotropical malaria vectors Anopheles gambiae s.s. necessitates the development of new strategies to control resistant mosquito populations. To test the efficacy of nets treated with repellent and insecticide against susceptible and insecticide-resistant An. gambiae mosquito populations, we impregnated mosquito bed nets with an insect repell...
BACKGROUND High coverage of personal protection measures that kill mosquitoes dramatically reduce malaria transmission where vector populations depend upon human blood. However, most primary malaria vectors outside of sub-Saharan Africa can be classified as "very zoophagic," meaning they feed occasionally (<10% of blood meals) upon humans, so personal protection interventions have negligible im...
the first records of anopheles fluviatilis resistance to ddt was reported in 1963 from india and to dieldrin from eastern saudi arabia in 1959. in southern iran, antimalaria measures began in 1950 and up to 1957 the area was under ddt residual house spraying at the rate of 2g /m2 one round/year. during 1958-59 dieldrin was used at 0.5 g/m2, 1or 2 rounds/year was applied in the lowland areas. in...
At a recent workshop, experts discussed the benefits, risks, and research priorities associated with using genetically manipulated insects in the control of vector-borne diseases.
In a survey on the anopheline fauna in highly malaria endemic areas of the Tirap district of Arunachal Pradesh, 7476 anophelines belonging to 17 species were collected, including seven species of anophelines which are recognized malaria vectors in India. Anopheles tessellatus and A. jamesii were recorded for the first time in this area. The parasitological survey revealed that the area was ende...
A focal outbreak of malaria at Bonta sub-centre of PHC Kilvani, the UT of Dadra & Nagar Haveli was reported during the month of August, 2014. Seven villages of the above block were affected. During the episode, around 757 fever cases were reported with Slide Positivity Rate (SPR) of 11.6%. The malaria epidemiological data for last three years from the subcentre area indicates that the area is e...
Malaria is one of the most important infectious diseases in the world, and it has many economic and social impacts on populations, especially in poor countries. Transmission-blocking vaccines (TBVs) are valuable tools for malaria eradication. A study on Anopheles gambiae revealed that polyclonal antibodies to carboxypeptidase B1 of A. gambiae can block sexual parasite development in the mosquit...
Irrigated urban agriculture (UA), which has helped alleviate poverty and increase food security in rapidly urbanizing sub-Saharan Africa, may inadvertently support malaria vectors. Previous studies have not identified a variable distance effect on malaria prevalence from UA. This study examines the relationships between self-reported malaria information for 3,164 women surveyed in Accra, Ghana,...
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