Cerebral malaria is a clinical manifestation of the brain during Plasmodium falciparum infection, which may lead to fatal outcomes if left unattended or delayed in therapeutic management. It is often accompanied by multi-organ complications such as renal failure, respiratory distress, jaundice, severe anemia etc., further raising the degree of mortality. Over the years, the management of severe...

BACKGROUND The geographic overlap between HIV-1 and malaria has generated much interest in their potential interactions. A variety of studies have evidenced a complex HIV-malaria interaction within individuals and populations that may have dramatic effects, but the causes and implications of this co-infection at the population level are still unclear. In a previous publication, we showed that t...

BACKGROUND The Papua New Guinea Department of Health recently shifted from a presumptive to a 'test and treat' malaria case management policy. This shift was supported by the widespread introduction of malaria rapid diagnostic tests in health facilities across the country. Health workers received training and job-aids detailing how to conduct and interpret a malaria rapid diagnostic test and ho...

Malaria, a disease known since ancient times and constantly struggled by human beings, still maintains its currency as an important cause of morbidity mortality today. Although no domestic cases have been observed in Turkey 2010, around 200-250 malaria originating from abroad are every year. Resistance to many parasitic drugs has developed over the years chloroquine resistance emerged 1970s. Ar...

The paucity of precise information on the burden of malaria among pregnant women has hampered effective lobbying for the inclusion of preventative strategies against malaria in Safe Motherhood Initiatives. This article reviews the evidence on the coincidental risks of malaria and anemia in Africa and attempts to estimate the probable burden of malaria-related severe anemia in this susceptible g...

BACKGROUND Efficient allocation of resources to intervene against malaria requires a detailed understanding of the contemporary spatial distribution of malaria risk. It is exactly 40 y since the last global map of malaria endemicity was published. This paper describes the generation of a new world map of Plasmodium falciparum malaria endemicity for the year 2007. METHODS AND FINDINGS A total ...

INTRODUCTION Home-based management of malaria is promoted as a major strategy for improving prompt delivery of effective malaria treatment in Africa. This study aimed to determine the proportion of children who tested positive for malaria with routine light microscopy among those whose mothers had made a home-based diagnosis in a rural community in Western Kenya. METHODOLOGY This cross-sectio...

malaria is a major problem in tropical and sub-tropical countries, with high morbidity and mortality. splenectomy makes patients more susceptible to serious bacterial and parasitic infections. we report for the first time in iran a fatal case of plasmodium vivax malaria, confirmed by microscopic and molecu­lar (semi-nested multiplex pcr) tests in a patient who had undergone splenectomy due to h...

Objective: It is the aim of this paper to estimate the provider’s cost of treating paediatric cases of Malaria in a rural African hospital. Furthermore, we intend to give some insights into the possibilities of improving the efficiency of treating children with this disease in order to support policy makers in the resource allocation process. Methods: The cost analysis was done in the district ...

Malaria remains as an important public health and a major cause of childhood death and paediatric hospital admission in sub-Saharan Africa. This prospective hospital based cross sectional study was conducted from April 2007 to April 2008. The main objective was to assess clinical manifestations and outcomes of severe malaria in children admitted to district hospital in Rungwe and Kyela in south...