Abstract Background Pregabalin abuse is increasing worldwide and frequently comorbid with another psychiatric disorders including generalized anxiety, major depression, personality disorders, suicide. Eighty-three patients meeting DSM-IV criteria for substance related to pregabalin were identified from the addiction clinic of El Khanka Psychiatric Hospital in Egypt this observational cross-sect...

Children with 22q11.2 deletion syndrome (22q11DS) present with congenital heart disease (CHD) and high prevalence of psychiatric disorders and neurocognitive deficits. Although CHD has been implicated in neurodevelopment, its role in the neuropsychiatric outcome in 22q11DS is poorly understood. We investigated whether CHD contributes to the high prevalence of psychiatric disorders and neurocogn...

BACKGROUND It is well known that most suicide cases meet criteria for a psychiatric disorder. However, rates of specific disorders vary considerably between studies and little information is known about gender and geographic differences. This study provides overall rates of total and specific psychiatric disorders in suicide completers and presents evidence supporting gender and geographic diff...

In a recent provocative Opinion article in Trends in Cognitive Sciences, Downar et al.1 (see also Goodkind et al.2) draw from quantitative metaanalyses of repositories of structural neuroimaging studies to propose a ‟common core” of brain regions whose function is disturbed in a wide variety of psychiatric disorders. Central to this core is the (dorsal) anterior cingulate cortex (ACC) and (ante...

INTRODUCTION Distinctions between rural and urban environments produce different frequencies of traumatic exposures and psychiatric disorders. We examine the prevalence of psychiatric disorders and frequency of trauma exposures by position on the rural-urban continuum. METHODS The National Comorbidity Survey Replication (NCS-R) was used to evaluate psychiatric disorders among a nationally-rep...

Family, twin and adoption studies have provided major evidence for the role of genetics in numerous psychiatric disorders including obsessive-compulsive disorder, panic disorder, major depressive disorder, bipolar disorder, schizophrenia and Alzheimer's disease. As the search for patterns of inheritance and candidate genes of these complex disorders continues, we review relevant findings from q...

OBJECTIVE To determine if the available data support the use of omega-3 essential fatty acids (EFA) for clinical use in the prevention and/or treatment of psychiatric disorders. PARTICIPANTS The authors of this article were invited participants in the Omega-3 Fatty Acids Subcommittee, assembled by the Committee on Research on Psychiatric Treatments of the American Psychiatric Association (APA...

Previous studies showed that psychiatric disorders such as major depression, bipolar disorders, and alcohol misuse are associated with an increased risk of ischemic stroke. However, the link between psychiatric disorders and stroke in the young population is rarely investigated. Using the Taiwan National Health Insurance Research Database, 2063 young adults aged between 18 and 45 years with isc...

Background: Thirty to forty percent of the patients referred to dermatologic clinics are estimated to have psychiatric problems. These patients either are those who have developed dermatologic problems as a consequence of their primary psychiatric disorders or those who have developed psychiatric disorders following their chronic and disfiguring dermatologic problems. The third group are psycho...

Psychoactive drugs are those psychotherapeutic drugs used to modify emotions and behavior in the treatment of psychiatric illnesses. This statement will limit its scope to drug selection guidelines for those psychoactive agents used during pregnancy for prevention or treatment of the following common psychiatric disorders: schizophrenia, major depression, bipolar disorder, panic disorder, and o...