نتایج جستجو برای: macrophage activation syndrome

تعداد نتایج: 1068365  

2013
P Guddeti Z Ahmed M Yiallourides

Introduction This is a case report of a 15 year old girl which presented with Pyrexia of Unknown Origin. She was initially treated for possible sepsis and then received treatment for Atypical Kawasaki’s. She was subsequently investigated for Haemophagocytic Lymphohistiocytosis (HLH). She was eventually diagnosed with Systemic Juvenile Idiopathic Arthritis (SoJIA) complicated with Macrophage Act...

Journal: :Frontiers in Immunology 2017

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2016
Maria Grandoch Christina Kohlmorgen Ariane Melchior-Becker Kathrin Feldmann Susanne Homann Julia Müller Lena-Sophia Kiene Jinyang Zeng-Brouwers Friederike Schmitz Nadine Nagy Amin Polzin Nina S Gowert Margitta Elvers Philipp Skroblin Xiaoke Yin Manuel Mayr Liliana Schaefer Lisa R Tannock Jens W Fischer

OBJECTIVE Thrombin signaling promotes atherosclerosis by initiating inflammatory events indirectly through platelet activation and directly via protease-activated receptors. Therefore, endogenous thrombin inhibitors may be relevant modulators of atheroprogression and cardiovascular risk. In addition, endogenous thrombin inhibitors may affect the response to non-vitamin K-dependent oral anticoag...

Journal: :Saudi medical journal 2007
Hakan H Celik Huseyin Tore Selcuk Tunali Ilkan Tatar Muhammed M Aldur

Griscelli syndrome is a rare disease characterized by pigment dilution, partial albinism, variable cellular immunodeficiency, and an acute phase of uncontrolled T-lymphocyte, and macrophage activation. Griscelli et al described this syndrome in 1978. Since then, only in approximately 60 cases have been reported, most from the Turkish, and Mediterranean population. In microscopic examination, si...

Journal: :Orvosi Hetilap 2021

Összefoglaló. A SARS-CoV-2-fertőzés ritka gyermekkori szövődménye a sokszervi gyulladás, angol terminológiával paediatric inflammatory multisystem syndrome (PIMS). Két vagy több szerv érintettségével járó, súlyos tünetekkel induló betegségről van szó, amelynek tünetei átfedést mutatnak Kawasaki-betegséggel, toxikus sokk szindrómával és makrofágaktivációs szindrómával. PIMS-betegek intenzív terá...

2008
C. RODRÍGUEZ - ESCALERA A. FERNÁNDEZ - NEBRO

1 Larroche C, Mouthon L. Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev 2004;3:69–75. 2 Ravelli A. Macrophage activation syndrome. Curr Opin Rheumatol 2002;14: 548–52. 3 Hibi S, Ikushima S, Fujiwara F et al. Serum and urine beta-2-microglobulin in hemophagocytic syndrome. Cancer 1995;75:1700–5. 4 Wellwood JM, Ellis BG, Price RG, Hammond K, Thompson AE, Jones NF. Urinary N-acetylbe...

2013
Cristina Rosário Gisele Zandman-Goddard Esther G Meyron-Holtz David P D’Cruz Yehuda Shoenfeld

BACKGROUND Over the last few years, accumulating data have implicated a role for ferritin as a signaling molecule and direct mediator of the immune system. Hyperferritinemia is associated with a multitude of clinical conditions and with worse prognosis in critically ill patients. DISCUSSION There are four uncommon medical conditions characterized by high levels of ferritin, namely the macroph...

Journal: :Rheumatology 2008
C Rodríguez-Escalera A Fernández-Nebro

1 Larroche C, Mouthon L. Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev 2004;3:69–75. 2 Ravelli A. Macrophage activation syndrome. Curr Opin Rheumatol 2002;14: 548–52. 3 Hibi S, Ikushima S, Fujiwara F et al. Serum and urine beta-2-microglobulin in hemophagocytic syndrome. Cancer 1995;75:1700–5. 4 Wellwood JM, Ellis BG, Price RG, Hammond K, Thompson AE, Jones NF. Urinary N-acetylbe...

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