STUDY OBJECTIVE To investigate the relation between body mass index and mortality in an unusually slim cohort. DESIGN Prospective cohort study. SETTING United Kingdom. PARTICIPANTS About 11,000 non-meat eaters and their meat eating friends and relatives, with a median age of 33 years were recruited between 1980 and 1984. More than 20% of the cohort had a self reported BMI below 20 kg/m(2)...

OBJECTIVE To explore the effect of the educational level of the head of household on the prevalence of malnutrition in Saudi children. METHODS The study was conducted over 2 years in 2004 and 2005 in all regions of the Kingdom of Saudi Arabia (KSA). The design consisted of a stratified multistage probability random sampling of the population of the KSA. The educational level of the heads of t...

BACKGROUND We hypothesize that premenopausal endogenous estradiol may be associated with age at menarche and adult overweight and obesity, potentially contributing to breast cancer risk. METHODS We assessed age at menarche by questionnaire among 204 healthy Norwegian women, aged 25-35 years. Measures of body composition included body mass index (BMI, kg/m(2)), waist circumference (WC, cm), wa...

BACKGROUND Achievement of durable responses in patients with relapsed/refractory peripheral T cell lymphoma (PTCL) is challenging with current therapies, and there are few data regarding the potential benefits of continuing treatment in patients with the best response of stable disease (SD). Histone deacetylase inhibitors are a novel class of drugs with activity in T cell malignancies. Romideps...

STUDY QUESTION Is the age of the father associated with placental weight or the ratio of placental weight to birthweight? SUMMARY ANSWER Placental weight and placental to birthweight ratio increased according to increasing paternal age, also after adjustment for maternal age. WHAT IS KNOWN ALREADY High paternal age and also high placental to birthweight ratio have been associated with adver...

Purpose: To evaluate the cost-utility and cost-effectiveness of Dr. Bart app compared to usual care in people with knee/hip OA, applying a health payer perspective. Methods: This economic evaluation was conducted alongside 6-month randomized controlled trial, involving 427 participants. The dr. is stand-alone eHealth application which invites users select pre-formulated goals (i.e. “tiny habits...

background: one of the important sites for extrapulmonary tb involvement is the skeleton. tuberculous spondylitis (pott’s disease) comprises 50-70% of the skeletal tuberculosis. methods: in this case series study, we prospectively investigated the result of anterior surgery alone (anterior debridement, fusion and instrumentation) in the patients with spinal tuberculosis. the patients with immat...

INTRODUCTION Infant body odor is subjectively pleasant to parents and activates reward areas in the brain. Hence, body odor perception might contribute to parental bonding. However, it is unknown whether the perceived pleasantness of children's body odor varies over the course of a child's development. METHODS Two hundred and thirty-five parents (M = 36.9 years, SD = 7.3) were asked to assess...

PURPOSE To compared the ultrasound findings of the lacrimal sac between subjects with normal lacrimal systems those with chronic dacryocystitis. METHODS A retrospective study of 10 subjects with a normal lacrimal system (Group 1) and 10 with chronic dacryocystitis (Group 2) diagnosed according to B-mode ultrasound with a 10-MHz transducer and the direct-contact technique (AVISO, Quantel Medic...

Aim of the current work was to examine developmental changes in adolescents' olfactory performance and personal significance of olfaction. In the first study olfactory identification abilities of 76 participants (31 males and 45 females aged between 10 and 18 years; M = 13.8, SD = 2.3) was evaluated with the Sniffin Stick identification test, presented in a cued and in an uncued manner. Verbal ...