A case of severe diarrhoea and steatorrhoea following chemotherapy and abdominal irradiation for lymphosarcoma, is described. Investigations demonstrated bile acid malabsorption, and treatment with cholesytramine and a low fat diet was successful. A questionnaire was sent to thirty-two subjects who had undergone similar treatment for similar pathology and failed to demonstrate any sustained alt...

The Effects of Two Alkaloids Derived from Vinca rosea on the Malignant Cells of Hodgkin’s Disease, Lymphosarcoma and Acute Leukemia in Vivo Alberto M. Marmont and Eugenio E. Damasio 1 Studies of Lymphocyte Kinetics in Man Seymour Perry, George L. Irvin, 111, and Jacqueline Whang 22 The Effects of Allografts of Thymic Epithelial Reticular Cells on the Lymphoid Tissues of Neonatally Thymectomized...

of primary cardiac tumors are benign tumors, such as myxoma.2) According to Prichard,3) the incidence of the cardiac rhabdomyosarcoma is lower than that of angiosarcoma, and nearly the same or slightly higher than that of other fibrosarcoma, reticulum cell sarcoma, and lymphosarcoma. We experienced an extremely rare case of rhabdomyosarcoma, which replaced the atrioventricular (A-V) node comple...

Informed Consent, the Placebo Effect, and The Revenge of Thomas Percival W. John Thomas, J.D., LL.M., M.P.H. 22 J. LEGAL MEDICINE 313 (2001). “I'm addicted to placebos. I could quit, but it wouldn't matter.” INTRODUCTION In 1957 a California man now known only as “Mr. Wright” was diagnosed with advanced lymphosarcoma cancer. When all known treatments proved ineffective, he entered a clinic, and...

Ribosomes were isolated and ribosomal RNA (rRNA) was prepared from leukemic cells derived from the venous blood of patients with acute myeloblastic leukemia, acute undifferentiated leukemia, subacute myelocytic leukemia, chronic lymphocytic leukemia, leukemic lymphosarcoma, leukemic reticuloendotheliosis, a cultured Burkitt lymphoma cell line, and phytohemagglutinin-stimulated normal lymphocyte...

RNase activity increases in P1798 lymphoid tumors main tained in BALB/c mi ce that are undergoing irevitro drug-induced regression. Corticosteroids, 5-fluorouracil, vincristine, vinblastine, methotrexate, and triethylenemelamine produce re gression of appropriate sublines of P1798 lymphosarcoma as well as an increase in RNase activity. Numerous other agents tested had no effect either on tumor ...

Epipodophyllotoxin (VM 26; 4'-demethyl-epipodophyllotoxin-beta-D-thenylidene glucoside) has been proved, in clinical screening, to be able to induce apparently complete remissions and pronounced though incomplete regressions in Hodgkin's disease, reticulosarcoma, and bladder cancer, as well as incomplete regressions in lymphosarcoma. Apparently complete regressions of malignant pleural effusion...

A total alkaloid and two purified alkaloid extracts of Alangium vitiense were found to be oncostatic for L1210 leukemia; the total alkaloid exerted a noticeable activity, and the purified extracts exerted a borderline activity. These two purified extracts are noticeably oncostatic for two other lymphoid neoplasias in mice, P388 leukemia and Gardner lymphosarcoma. These compounds are not active ...

In both the cases described, painful ophthalmoplegia was the first indication of infiltration of the cavernous sinus by a lymphosarcoma. The onset of symptoms and the course of the disease were different in the two cases. CT scan which has been the crucial investigation for detecting lymphomas in the cavernous sinus, was normal in the early stages. Symptomatic remission could be obtained with t...

Rearrangement in the c-myb locus of each of four independently derived BALB/c plasmacytoid lymphosarcoma (ABPL's) is due to the insertion of a defective Moloney murine leukemia virus (M-MuLV) into a 1.5-kilobase-pair stretch of cellular DNA at the 5' end of the v-myb-related sequences. This retroviral insertion is associated with abnormal transcription of myb sequences and probably represents a...