Sinus histiocytosis with massive lymphadenopathy is a well recognised, but rare cause of lymphadenopathy in the first decade of life. Three cases presenting with nodal disease are described. The eyelids were involved in one case. The clinical, laboratory, and biopsy findings are discussed and compared with previously reported cases.

1. Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy: a newly recognized benign clinicopathological entity. Arch Pathol. 1969;87 (1):63-70. 2. Foucar E, Rosai J, Dorfman R. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity. Semin Diagn Pathol. 1990;7(1):19-73. 3. Eisen RN, Buckley PJ, Rosai J. Immunophenotypic characterization of ...

By CHARLES P. DUVALL, PAUL P. CARBONE, WILLIAM R. BELL, JACQUEUNE WILANG, J. H. TJI0 AND SEYMOUR PERRY A MINOR DEGREE OF LYMPHADENOPATHY occurs in relatively few cases of patients with chronic myelocytic leukemia ( CML ).‘ Marked lymph node enlargement may occur late in the course of the disease, usually with the development of the myeloblast crisis, and may be considered a poor prognostic sign...

Kawasaki disease (KD) is a vasculitis that mostly affects children under 5 years of age. This article presents a 2.5-year-old boy who presented with 6 days of fever, generalized maculopapular rash, bilateral non-exudative conjunctivitis, cracked lips, right cervical lymphadenopathy, erythematous extremities, and perianal desquamation. Laboratory studies showed leukocytosis and sterile pyuria. B...

INTRODUCTION The clinical presentation of carcinoma of the cervix as cervical lymphadenopathy has not been described before. We report a case of this unusual manifestation of cervical cancer. CASE PRESENTATION A 51-year-old woman presented to our Head and Neck department with cervical lymphadenopathy. A positron emission tomography scan revealed the primary tumour to be in the cervix and a ce...

Although rapid diagnostic testing is essential in suspicious peripheral lymphadenopathy, delays in accessing them can be considerable. We investigated the usefulness of an internist-led outpatient quick diagnosis unit (QDU) in assessing patients with unexplained peripheral lymphadenopathy, focusing on the characteristics, diagnostic, and treatment waiting times of those with malignancy. Patient...

Introduction: Nodes that are aberrant in their size, consistency, or number referred to as lymphadenopathy. Study Duration: Current research was carried out at Surgery Department of Chandka Medical College (CMC) & Teaching Hospital, Larkana starting from March 2019 September 2020. Subjects Methods: After taking written informed consent, 162 patients included the study after fulfilling inclu...

leishmaniasis is an endemic parasitic disease in iran. this paper reports the case of a 5-yr-old boy who presented with multiple isolated cervical lymphadenopathy for several months with no history of fever and no signs or symptoms. in an excisional lymph node biopsy, leishmania parasites were histologically detected. thus, leishmaniasis should be included in the differential diagnosis of isola...

Toxoplasmosis is a parasitic infection divided into congenital and acquired forms. In the latter form, malaise, fatigue, and lymphadenopathy are commonly found, and submandibular lymphadenopathy is sometimes a manifestation. In children, cervical lymph nodes usually are affected. This is a case of a 13-year-old boy suffering from acquired toxoplasmosis, in which submandibular lymphadenopathy wa...

Fig. 1. Cervical computed tomography (CT) images. (A) Cervical CT reveals right cervical lymphadenopathy. (B) Cervical enhanced CT reveals considerable improvement in right cervical lymphadenopathy after 3 cycles of chemotherapy with tetrahydropyranyl doxorubicin (50 mg on day 1), cyclophosphamide (750 mg on day 1), vincristine (1.6 mg on day 1), and prednisolone (50 mg on days 1–5). (C) Cervic...