Several medicinal plants have been documented for their haematological effects either at low or high concentration but very little is known about Aspilia africana. The aim of the study was to investigate the acute effects of aqueous leaf extract of Aspilia africana at different concentrations on some haematological parameters in rats. Following 14 days of oral administration of aqueous extract ...

Effect of graft source on unrelated donor haemopoietic stem-cell trans-plantation in adults with acute leukaemia: a retrospective analysis. al. Unrelated transplantation for poor-prognosis adult acute lym-phoblastic leukemia: long-term outcome analysis and study of the impact of hematopoietic graft source. R, et al. Favorable outcome of unrelated cord blood transplantation for Philadelphia chro...

Australia Pulmonary disease in non-Hodgkin's lymphoma is known to occur in 10-25% of patients,' 2 but the exact diagnosis during life remains difficult and usually depends on exclusion of other possibilities-for example, infection and haemorrhage-or the use of techniques such as fibreoptic bronchoscopy, bronchial brushing, and needle biopsy.3 Cytological examination of the sputum, which is a mu...

Three genetic lines of turkeys were compared for their responses to Escherichia coli challenge following dexamethasone injection (Dex) or E. coli challenge preceding transport stress (TS). The turkey lines were a slow growing line selected for increased egg production (Egg line), a fast growing line selected for increased 16-wk BW (F line), and a commercial line (Comm line). At 14 wk of age, th...

cooperate with VEGFR-3 in lymphatic endothe-lial cell migration and proliferation. Whereas VEGF-C is essential in mouse lymphatic vascu-lar development, it remains to be resolved to what extent the lack of VEGFR-2 binding accounts for the dispensable role of VEGF-D in this process. 5,6 Elucidation of the receptor-binding pattern of Xenopus VEGF-D and finding whether it explains the functional d...

U ncontrolled lymphoproliferation is a characteristic feature of lymphomas and leukemias. Nonmalignant lym-phoproliferative diseases are also observed in humans as well as in lpr (lymphoproliferation) and gld (generalized lymphad-enopathy) mice. The discoveries that spontaneous mutations of Fas (APO-1/CD95) or its ligand (FasL) were associated with the lpr and gld phenotypes led to a satisfying...

It seems very interesting and also strange that a malignant disease can be treated with antibiotics and acid suppressant combination therapy, rather than chemotherapy or radiotherapy. Infectious agents such as hepatitis B virus and hepatitis C virus, Epstein-Barr virus, Helicobacter pylori, and herpes simplex virus are well known causative agents for chronic inflammation associated cancers incl...

been recognized for many years (1, 7, 11). Estro gen-treated mice of some strains have a higher incidence of lyrnphomas than untreated controls (5, 6), andtestosterone propionate decreased the incidence of such tumors when given with estro gen (5). Sex differences in the incidence of lym phomas in untreated mice have not been noted generally, but in mice of one strain, at least, fe males showed...

The recirculation of naive lymphocytes from the blood to LNs then back to the blood through the efferent lym-phatics increases the likelihood that rare antigen-specific cells will encounter their specific antigen. Circulating lym-phocytes enter the LNs at specialized postcapillary venules known as high endothelial venules (HEVs). Homing to HEVs is thought to occur in three steps. First, lymphoc...

A recent article entitled " Prognostic Signifi cance of a Short Sequence Insertion in the MCL-1 Promoter in Chronic Lym-phocytic Leukemia " identifi ed two novel sequence variants of the MCL-1 promoter within lymphocytes from chronic lym-phocytic leukemia (CLL) patients but not within noncancerous tissue from the same individuals or in lymphocytes from 18 healthy control subjects (1). This resu...