Left ventricular (LV) hypertrophy leads to diastolic dysfunction. Standard Doppler transmitral and pulmonary vein (PV) flow velocity measurements are preload dependent. New techniques such as mitral annulus velocity by Doppler tissue imaging (DTI) and LV inflow propagation velocity measured from color M-mode have been proposed as relatively preload-independent measurements of diastolic function...

The authors propose a new approach for tracking the deformation of the left-ventricular (LV) myocardium from two-dimensional (2-D) magnetic resonance (MR) phase contrast velocity fields. The use of phase contrast MR velocity data in cardiac motion problems has been introduced by others (N.J. Pelc et al., 1991) and shown to be potentially useful for tracking discrete tissue elements, and therefo...

The spectral Doppler mitral flow pattern, alone or combined with tissue Doppler mitral annulus velocity, can be used to predict left ventricular (LV) filling pressure in humans, whereas invasive hemodynamic measurements are still required in the rat. This study was undertaken to assess whether LV end-diastolic pressure (LVEDP) can be estimated using Doppler echocardiography in the rat after myo...

BACKGROUND The precise mechanism of takotsubo-like left ventricular (LV) dysfunction remains unclear. METHODS AND RESULTS Eight consecutive patients with takotsubo-like LV dysfunction were studied. In the acute phase and 3 weeks later, the coronary flow velocity spectrum and coronary flow velocity reserve (CFVR) were recorded by Doppler guidewire. The deceleration time of diastolic velocity (...

STUDY OBJECTIVES Early diastolic mitral annular velocity (E') by tissue Doppler echocardiography (TD) has been reported to be a load-independent index of left ventricular (LV) diastolic function, allowing the early diastolic mitral inflow velocity (E)/E' ratio to be used clinically to predict LV filling pressures. However, preload independence of E' has remained controversial, and E/E' may not ...

Methods 43 patients with ischemic heart failure (61±11years) and 22 healthy volunteers (29±13years) were included. Vp by Color M-mode echocardiography (Vp-echo), was measured according to current recommendations (Figure 1). VE-MRI was performed on a 1.5 or 3.0 Tesla MRI system during free breathing, with single-direction in-plane velocity-encoding in phase-encoding direction, angulated parallel...

Few data are available regarding the effects of exercise training upon cardiac structure and performance in man. We evaluated the echograms of 24 normals before (PRE) and after (POST) 11 weeks of endurance exercise training. Conditioning consisted of a walk-jog-run protocol at 70% maximal heart rate for one hour four days per week. Training reduced heart rate and increased maximal duration and ...

The progression of hypertensive involvement toward heart failure includes myocardial fibrosis and changes of left ventricular (LV) geometry. In the presence of these abnormalities, diastolic abnormalities occur and are defined as LV diastolic dysfunction (DD). They include alterations of both relaxation and filling, precede alterations of chamber systolic function and can induce symptoms of hea...

PURPOSE To assess turbulent kinetic energy (TKE) within the left ventricle (LV) of healthy subjects using novel 4D flow magnetic resonance imaging (MRI) methods and to compare TKE values to those from a limited group of patients with a spectrum of dilated cardiomyopathy (DCM). MATERIALS AND METHODS 4D flow and morphological MRI data were acquired in 11 healthy subjects and 9 patients with dif...

CONTEXT Adiponectin inhibits protein synthesis in cardiac myocytes, thereby opposing the effect of cardiac workload and trophic factors (in particular, insulin) on left ventricular (LV) mass and wall thickness (WT). OBJECTIVE We tested whether adiponectin and its isoforms are related to LV mass, WT, and function independently of metabolic factors. DESIGN This was a cross-sectional study. ...