Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all around the world. It has been identified as the fourth leading cause, which will rise globally to the third place, before the end of 2020. It is estimated that more than 12 million adults suffer from COPD in the USA and 24 million patients have an impaired lung function, which may lead to the developmen...

We present a case report of a 28-year-old primigravida with a singleton pregnancy complicated by a fetal bronchogenic cyst compressing the left mainstem bronchus with resultant hyperinflation of the entire left lung and rightward mediastinal shift. An ex utero intrapartum treatment to resection of the fetal bronchogenic cyst via a fetal thoracotomy was performed at 36 weeks' gestational age, ci...

Congenital pulmonary airway malformation (CPAM) is a rare entity. Anesthetic management for lobectomy is challenging due to sudden hemodynamic collapse which may occur during induction and ventilatory problems due to hyperinflation of cystic lesions with positive pressure ventilation. We discuss successful anesthetic management of two infants with CPAM posted for pneumonectomy with a brief ment...

The role of dynamic hyperinflation (DH) in exercise limitation in chronic obstructive pulmonary disease (COPD) remains to be defined. We examined DH during exercise in 105 patients with COPD (FEV(1) = 37 +/- 13% predicted; mean +/- SD) and studied the relationships between resting lung volumes, DH during exercise, and peak oxygen consumption (VO(2)). Patients completed pulmonary function tests ...

Dyspnea (respiratory difficulty) and activity limitation are the primary symptoms of chronic obstructive pulmonary disease (COPD) and progress relentlessly as the disease advances, contributing to reduced quality of life. In COPD, the mechanisms of dyspnea are multifactorial, but abnormal dynamic ventilatory mechanics are believed to play a central role. In flow-limited patients with COPD, dyna...