نتایج جستجو برای: long qt سندرم

تعداد نتایج: 790950  

Journal: :Diabetes care 2002
Paul E Valensi Nicolas B Johnson Pierre Maison-Blanche Fabrice Extramania Gilbert Motte Philippe Coumel

OBJECTIVE Prolongation of the QT interval and increased QT dispersion are associated with a poor cardiac prognosis. The goal of this study was to assess the long-term influence of the autonomic nervous system on the heart rate dependence of ventricular repolarization in patients with diabetic autonomic neuropathy (DAN). RESEARCH DESIGN AND METHODS We studied 27 subjects (mean age 51.8 years) ...

2009
Patrick Campbell Suzanne Dawson Jaweed Wali Brian Kenny Michael CR Whiteside

implanted due to continued risk of arrhythmia from electrolyte loss from the ileostomy. The QTc came down to 454ms and BNP fell to 179pg/ml at discharge. QT prolongation is the surface ECG manifestation of abnormal repolarisation of myocardial cells due to problems with cellular ion channels. The disorder is classified as either congenital or acquired. Acquired QT prolongation may be due to: 1....

2003
E Schulze-Bahr H Fenge D Etzrodt W Haverkamp G Mönnig H Wedekind G Breithardt H-G Kehl

Intrauterine and neonatal manifestations of congenital long QT syndrome are associated with a high cardiac risk, particularly when atrioventricular block and excessive QT prolongation (. 600 ms) are present. In a female newborn with these features, treatment with propranolol and mexiletine led to complete reduction of arrhythmia that was maintained 1.5 years later. High throughput genetic analy...

Journal: :Circulation. Arrhythmia and electrophysiology 2009
Hideki Itoh Tomoko Sakaguchi Wei-Guang Ding Eiichi Watanabe Ichiro Watanabe Yukiko Nishio Takeru Makiyama Seiko Ohno Masaharu Akao Yukei Higashi Naoko Zenda Tomoki Kubota Chikara Mori Katsunori Okajima Tetsuya Haruna Akashi Miyamoto Mihoko Kawamura Katsuya Ishida Iori Nagaoka Yuko Oka Yuko Nakazawa Takenori Yao Hikari Jo Yoshihisa Sugimoto Takashi Ashihara Hideki Hayashi Makoto Ito Keiji Imoto Hiroshi Matsuura Minoru Horie

BACKGROUND Drugs with I(Kr)-blocking action cause secondary long-QT syndrome. Several cases have been associated with mutations of genes coding cardiac ion channels, but their frequency among patients affected by drug-induced long-QT syndrome (dLQTS) and the resultant molecular effects remain unknown. METHODS AND RESULTS Genetic testing was carried out for long-QT syndrome-related genes in 20...

Journal: :British heart journal 1994
R A Cooke J B Chambers R Singh G J Todd N C Smeeton J Treasure T Treasure

OBJECTIVES To determine the incidence of a long QT interval as a marker for sudden death in patients with anorexia nervosa and to assess the effect of refeeding. To define a long QT interval by linear regression analysis and estimation of the upper limit of the confidence interval (95% CI) and to compare this with the commonly used Bazett rate correction formula. DESIGN Prospective case contr...

Journal: :Heart 1999
M H Wu F C Hsieh J K Wang M L Kau

Two patients with a novel variant of long QT syndrome are described. The clinical course was characterised by an in utero onset of ventricular tachycardia and atrioventricular block (at 26 and 30 weeks' gestational age, respectively), and an association with a ventricular septal defect. Studies of both patients' families identified relatives with prolonged QT interval, syncope, or sudden death....

2016
Osmar Antonio Centurión

J Cardiol Curr Res 2016, 5(5): 00176 the declining inflow of sodium and calcium. These ion currents utilize specific channels that are under the influence of multiple factors. The long QT syndrome is characterized by QT interval prolongation and a tendency to develop a potentially lethal ventricular tachycardia [1,2]. Several anti-arrhythmic drugs, as well as some non-cardiac medications, block...

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