The biological potential of prostate cancer is highly variable and cannot be satisfactorily predicted by histopathological criteria alone. Therefore, additional and more precise information is desirable. Although angiogenesis has been suggested as being of prognostic importance in many human cancers, and MUC1, also known as episialin, was thought to be responsible for the development of metasta...

OBJECTIVES To analyse the clinical utility of a prediction model incorporating both clinical information and a novel biomarker, p2PSA, in order to inform the decision for prostate biopsy in an Irish cohort of men referred for prostate cancer assessment. PATIENTS AND METHODS Serum isolated from 250 men from three tertiary referral centres with pre-biopsy blood draws was analysed for total pros...

background defining the optimal prostate-specific antigen threshold to identify the patients at the highest risk of prostate cancer has always been a controversial issue. objectives this study aims to analyze the diagnostic value of psa and also evaluate the relationship between psa (prostate-specific antigen) and bmi (body mass index) as well as psa and prostate size and volume in asymptomatic...

background: the normal prostate-specific antigen (psa) level in patients with urethral catheterization is a controversy. we designed this study to investigate the effect of nontraumatic urethral catheterization without urinary retention on serum psa. materials and methods: seventy patients scheduled for urethral catheterization before elective surgeries were randomly selected and included in th...

The biological potential of prostate cancer is highly variable and cannot be satisfactorily predicted by histopathological criteria alone. Therefore, additional and more precise information is desirable. Although angiogenesis has been suggested as being of prognostic importance in many human cancers, and MUC1, also known as episialin, was thought to be responsible for the development of metasta...

Aims: To determine the molecular properties of common antihistamines and non-steroidal antiinflammatory agents (NSAIDs). To identify interrelationships among these two groups of drugs utilizing pattern recognition methods and statistical analysis. Study Design: After determination of molecular properties, values thereof are examined using pattern recognition methods and other numerical analysis...

background: breast cancer is the most common cancer in women. prostate‑specifc antigen  (psa) is a marker of prostate gland malignancy, which has been considered in cases with breast cancer in recent years. the goal of this study was to determine total and free psa levels in cases with malignant and benign breast lesions. methods:   in  this case–control study, ninety women with histological pr...

We consider using observational data to estimate the effect of a treatment on disease recurrence, when the decision to initiate treatment is based on longitudinal factors associated with the risk of recurrence. The effect of salvage androgen deprivation therapy (SADT) on the risk of recurrence of prostate cancer is inadequately described by the existing literature. Furthermore, standard Cox reg...