IMPORTANCE Although most cases of cutaneous squamous cell carcinoma (CSCC) are easily cured with surgery or ablation, a subset of these tumors recur, metastasize, and cause death. We conducted the largest study of CSCC outcomes since 1968. OBJECTIVE To identify risk factors independently associated with poor outcomes in primary CSCC. DESIGN A 10-year retrospective cohort study. SETTING An...

One hundred twenty-six rectal cancers were operated upon in the First Department of Surgery, Nagasaki University School of Medicine. Local recurrence occurred in thirty-three (26.2%). In this study, contributing factors in causing local recurrence were local excision of the surgical approach, advanced stage, depth of cancer invasion, location of carcinoma of the rectum below the peritoneal refl...

The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human renin gene develop the PE syndrome, whereas those of the opposite cross do not. We used this model to study the role of Ang II in trophoblast in...

Vascular endothelial growth factor-C (VEGF-C) is considered to be a specific factor promoting lymphangiogenesis. There have been reports of a positive correlation between local recurrence of rectal carcinoma and lymphatic invasion by the tumor. The aim of this study was to determine the clinical significance of VEGF-C expression for identifying lymphangiogenesis as a predictor of the local recu...

Stage-structured models that integrate demography and dispersal can be used to identify points in the life cycle with large effects on rates of population spatial spread, information that is vital in the development of containment strategies for invasive species. Current challenges in the application of these tools include: (1) accounting for large uncertainty in model parameters, which may vio...

• With growing concerns over serious ecological problems, a particular challenge is to reveal the complex mechanisms underlying rapid expansion of invasive species. Ageratina adenophora is of particular interest in addressing this question. • We used geographic information systems and logistic regression to identify the geographic and environmental factors contributing to the presence of A. ade...

Many introduced species engage in intraguild predation (IGP), the consumption of species with which they compete for shared resources. While the factors influencing local persistence of IG predator and prey species are well-understood, using these factors to predict the invasion speed of an introduced IG predator has received less attention. Existing theory predicts that native competitors slow...

Tumors of chest wall represent a variant entity. Most of them arise from metastasis of malignant tumors or from local invasion by contiguity. However, non-Hodgkin's lymphomas of the chest wall are extremely rare; only a few cases have been reported in the literature. We report a case about a Moroccan woman, with non-Hodgkin null phenotype lymphoma of the chest, treated successfully with CHOP (c...

Caulerpa racemosa is a tropical green alga introduced into the Mediterranean probably as an immigrant from the Red Sea. This study evaluated the modifications caused by C. racemosa invasion on the structure of the benthic macroalgal community near Leghorn (northwestern Mediterranean). To achieve this objective, we studied invasion by C. racemosa of algal assemblages on 2 different substrata by ...

Similar to the increased number of studies on invasive plants and animals in terrestrial and aquatic ecosystems, many reports were recently published on the invasion of Nostocales (cyanobacteria) to freshwater environments worldwide. Invasion and proliferation of Nostocales in new habitats have the potential to significantly alter the structure of the native community and to modify ecosystem fu...