Accumulating evidences indicate that long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) play important roles in tumorigenesis. However, the mechanisms remain largely unknown. To explore lncRNAs and circRNAs expression profiling and their biological functions in bladder cancer, we surveyed the lncRNA/circRNA and mRNA expression profiles of bladder cancer and para-cancer tissues using mic...

Long non-coding RNA (lncRNA) is a kind of non-coding RNA with transcripts more than 200 bp in length. LncRNA can interact with the miRNA as a competing endogenous RNA (ceRNA) to regulate the expression of target genes, which play a significant role in the initiation and progression of tumors. In this study, we explored the functional roles and regulatory mechanisms of lncRNAs as ceRNAs in gastr...

عاطقلا طبر ي يذ لا ة يبرهكلا ىو قلا ماظنل يكيمانيدلارارقتسلال ةضيفتسم ةيلمع ةسارد ثحبلا اذه مدقي ني ب ة لوقنملا ةرد قلا ةدا يز ى لع ك لذ ريثأ ت و ةيدوعس لا ءا برهآ ةآر ش ن م ط سولأا عا طقلا و يقرش لا نيعاطقلا ، ىوقلا مظن تاتبثم طبض للاخ نم كلذو . دقل شم ةغايص مت ةلك طبض ةروص ىف تاتبثملا هذه ةلثمأ ةلكشم . ماظنلا ءادأ نيسحتل ك لذو ةدر فنملا ماظنلا ميق ىلع نادمتعت فده يتلاد حارتقا مت دقلو . د قلو ...

يفكي هنأ نيبن ،ثحبلا اذه يف ةيقفأ حئارش تاطاقسإ هيمسن ام لثم باسحلا ةلهس ملاعم مادختسا ايلآ ةعوبطملا فورحلا ىلع يئوضلا فرعتلا ةلأسم ةءافكب لحت يكل ةيسأرو . ةرجش مادختساب فرعتلا متي حاجنلا لدعم ةدايزل ىرخأ تافاضإ عم ةدمعأو فوفص فذحو ميعنتو عوجر تايلآب ةموعدم رارق . و مدختسن ماظنلا بيردتل طخ نم زومر Times New Roman . دق فذحلاو ميعنتلاو عوجرلا ليعفت نإ لاًدعم ققح حجان اً زواجت 98 % نم لقأ فرعت نمزب ...

Recognizing TimeML events and identifying their attributes, are important tasks in natural language processing (NLP). Several NLP applications like question answering, information retrieval, summarization, and temporal information extraction need to have some knowledge about events of the input documents. Existing methods developed for this task are restricted to limited number of languages, an...

In this study, Four Wave Mixing (FWM) characteristics in photonic crystal fibers are investigated. The effect of channel spacing, phase mismatching, and fiber length on FWM efficiency have been studied. The variation of idler frequency which obtained by this technique with pumping and signal wavelengths has been discussed. The effect of fiber dispersion has been taken into account; we obtain th...

يمومع باي تيعقوم متسيس كي تقد 3 رد متسيس وردوخ يربوان ياه يم ريثأت يفلتخم لماوع زا زا تـسا مزلا لـيلد نيمه هب و دريذپ شور دومن هدافتسا وردوخ هدش نييعت تيعقوم رد تقد شيازفا تهج هشقن قيبطت ياه . متسيس رد هشقن قيبطت وردوـخ يربواـن ياـه دراد هدهع رب ار رهش هشقن يوررب وردوخ يلعف تيعقوم نييعت هفيظو . رد هـشقن قيبطت هلأسم لح يارب يبيكرت متيروگلا كي هلاقم نيا متسيس رد يم داهنشيپ وردوخ يربوان يا...

Paclitaxel is a chemotherapeutic substance that administered for treatment of an extensive spectrum human malignancies. In spite its potent short-term effects against tumor cells, resistance to paclitaxel occurs in number patients precluding long-term application these patients. Non-coding RNAs have been shown influence response cancer cells this agent via different mechanisms. Mechanistically,...

Circular RNAs (circRNAs) are a class of endogendous RNAs that form a covalently closed continuous loop and exist extensively in mammalian cells. Majority of circRNAs are conserved across species and often show tissue/developmental stage-specific expression. CircRNAs were first thought to be the result of splicing error; however, subsequent research shows that circRNAs can function as microRNA (...

Compared to their protein-coding counterparts, almost nothing is known about the role of long noncoding RNAs (lncRNAs) in cardiac fibrosis. In the current report, Liang and Pan et al. characterized the pro-fibrotic lncRNA PFL in respect to cardiac fibrosis in mice. PFL was upregulated in the hearts of mice after myocardial infarction and in fibrotic cardiac fibroblasts. Moreover, PFL competitiv...