Abstract A simple chain‐extension reaction using diisocyanate as a chain extender was adopted to increase the molecular weight of low‐molecular‐weight (LMW) poly(lactic acid) (PLA) synthesized via direct polycondensation and recover commercial PLA after service life. The slow between carboxylic acid terminus successfully accelerated Mg(II) catalyst, affording linear chain‐extended (cePLA) conne...

Cyclin E is a G1 cyclin essential for G1 to S-phase transition of the cell cycle with a profound role in oncogenesis. In tumor cells and tissues, cyclin E is overexpressed and present in its lower molecular weight (LMW) isoforms, and it can be used as a prognosticator for poor patient outcome. In this study, we have examined differences in the processing of cyclin E between normal mammary epith...

AIMS The relevance of lipoprotein(a) [Lp(a)] concentrations and low-molecular-weight (LMW) apo(a) phenotypes in peripheral arterial disease (PAD) has only been investigated by few studies. Therefore, we analysed this association in three independent cohorts and performed a Mendelian Randomization approach using instrumental variable regression. METHODS AND RESULTS Lp(a) concentrations, apo(a)...

Advanced glycation end-products (AGE) have been implicated in aging and the pathogenesis of diabetic complications, inflammation, Alzheimer's disease, and cancer. AGE engage the cell surface receptor for AGE (RAGE), which in turn elicits intracellular signaling, leading to activation of NF-κB to cause deterioration of tissue homeostasis. AGE are not only formed within our bodies but are also de...

A new method of sequential extraction of proteins followed by quantitative and qualitative determination by reverse-phased high-performance liquid chromatography (RP-HPLC) was used to analyse the effect of environmental conditions (3N fertilisation rates, two varieties, two sites and two growing seasons) on quantitative and qualitative variation of wheat storage proteins. The results showed tha...

Background: intra-articular (IA) injections of hyaluronic acid (HA) preparations are one conservative treatment the knee osteoarthritis (OA). However, results this inconsistent. Objectives: to evaluate effectiveness HA with different molecular weights and in combination chondroitin sulfate (HS) for IA patients stage I-III OA. Methods: were performed 160 primary post-traumatic OA stages at depar...

The lesser mealworm (LMW, Alphitobius diaperinus (Panzer); Coleoptera: Tenebrionidae) is increasingly used as a novel food and feed source. materials on which this insect species reared may contain residues of insecticides from agricultural use. objective study was to determine whether selected insecticides, spiked the substrate, could bioaccumulate in LMW and/or affect growth or survival. Inse...

Alginate hydrogels are a commonly used substrate for in vitro 3D cell culture. These naturally derived biomaterials highly tunable, biocompatible, and can be designed to mimic the elastic modulus of adult brain at 1% w/v solution. Recent studies show that molecular weight alginate affect viability differentiation. The relationship between weight, viscosity ratio G:M monomers is complex, balance...

The Dasypyrum villosum gene bank collection, comprising 32 accessions, was characterized morphologically and genetically for resistance to leaf diseases quality parameters of seeds with specific accent protein polymorphism starch composition. collected material represented nearly the whole distribution area in Mediterranean. For SSR analysis, a set 40 markers wheat selected. A matrix distances ...

BACKGROUND Newborn resuscitation with 100% oxygen is associated with oxidative-nitrative stresses and inflammation. The mechanisms are unclear. Hyaluronan (HA) is fragmented to low molecular weight (LMW) by oxidative-nitrative stresses and can promote inflammation. We examined the effects of 100% oxygen resuscitation and treatment with the antioxidant, N-acetylcysteine (NAC), on lung 3-nitrotyr...