M. de Naurois, G. Dubus, S. Funk, G. Rowell, P.M. Chadwick for the H.E.S.S. Collaboration (a) LPNHE IN2P3 CNRS Universities Paris VI & VII, Paris, France (b) LLR IN2P3 CNRS, Ecole Polytechnique, Palaiseau, France (c) Max-Planck-Institut für Kernphysik, Heidelberg, Germany (d) University of Durham, Department of Physics, Durham, U.K. Presenter: M. de Naurois ([email protected]), fra-denaurois-M-...

Supported by: Main financial support for the MRC Myeloma IX clinical trial was from the UK Medical Research Council, with additional funding in the form of unrestricted educational grants from Novartis, Schering Health Care, Chugai, Pharmion, Celgene and Ortho Biotech. The LLR UKMF Cytogenetics group was supported by Leukemia and Lymphoma Research. The Institute of Cancer Research received fina...

Fixed tobramycin (mg/kg) dosing is often inappropriate in patients with cystic fibrosis (CF), as pharmacokinetics are highly variable. The area under the concentration-time curve (AUC) is an exposure metric suited to monitoring in this population. Bayesian strategies to estimate AUC have been available for over 20 years but are not standard practice in the clinical setting. To assess their suit...

Question: What explains the differences in ratios of diploid (LR) and two types of triploid frogs (LLR, LRR) among all-hybrid frog populations? Hypothesis: Ecological conditions favouring one (LL) or the other (RR) parental species also favour those triploids that carry two copies of the respective genome (dosage effect), whereas diploids dominate under intermediate conditions. Organism: Europe...

Since 1969, Lunar Laser Ranging (LLR) data have been collected by various observatories and analysed different analysis groups. In the recent years, observations with bigger telescopes (APOLLO) at infra-red wavelength (OCA) are carried out, resulting in a better distribution of precise LLR over lunar orbit observed retro-reflectors on Moon. This is great advantage for investigations analysis. T...

A key goal of sediment management is the quantification suspended load (SSL) in rivers. This research focused on a comparison different means estimation includes rating curves (SRC) and soft computing techniques, i.e., local linear regression (LLR), artificial neural networks (ANN) wavelet-cum-ANN (WANN) method. Then, techniques were applied to predict daily SSL at Pirna Magdeburg Stations Elbe...

Reinforcement Learning (RL) is a popular method in machine learning. In RL, an agent learns a policy by observing state-transitions and receiving feedback in the form of a reward signal. The learning problem can be solved by interaction with the system only, without prior knowledge of that system. However, real-time learning from interaction with the system only, leads to slow learning as every...

BACKGROUND Restoration of a neutral mechanical axis is a primary goal of total knee replacement (TKR). A mechanical axis within 3° of neutral has been correlated with improved implant longevity, function, and patient satisfaction. We hypothesize that the immediate post-operative radiograph is an unreliable method of measuring alignment following TKR surgery. METHODS Seventy-five consecutive p...

BACKGROUND Few data regarding survival or pattern of recurrence after laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) on cirrhosis have been reported so far. METHODS A retrospective analysis of a prospectively maintained database of 109 laparoscopic interventional procedures performed for HCC in cirrhotic liver between 2000 and 2008 was conducted. RESULTS Sixty-five pa...