OBJECTIVES To examine whether incidence of colorectal malignancy is increased in Australasian liver transplant recipients compared with the general population of Australia, and to assess the characteristics and outcomes of colorectal malignancy in this patient group. DESIGN, SETTING AND PATIENTS Data on patients who underwent orthotopic liver transplantation (OLTx) and had a diagnosis of de-n...

UNLABELLED The aim of this study was to determine the prevalence of hepatocellular carcinoma (HCC) in our liver transplant clinic, and describe the risk factors, predictors and treatment outcomes of primary liver cancer. METHODS 459 of 469 records of patients attending the UPR Liver Transplant Clinic from September 1999 to January 2005 were reviewed. Frequency distributions were computed to d...

Development of renal failure requiring renal replacement therapy (RRT) in the cirrhotic patient is a devastating complication. Survival without RRT is less than 10% on average at 6 months. However, it is now appreciated that all renal failure in this group of patients is not due solely to hepatorenal syndrome, and the cause of the renal failure affects the prognosis. This paper reviews the prog...

BACKGROUND Following liver transplantation, patients require lifelong immunosuppressive care and monitoring. Computerized clinical decision support (CDS) has been shown to improve post-transplant immunosuppressive care processes and outcomes. The readiness of transplant information systems to implement computerized CDS to support post-transplant care is unknown. OBJECTIVES a) Describe the cur...

GOALS To define the influence of nonalcoholic fatty liver disease (NAFLD) and its associated comorbidities on liver transplant outcomes. BACKGROUND NAFLD cirrhosis is an increasing indication for transplant. The transplant outcomes of NAFLD patients with metabolic syndrome comorbidities remain unclear. STUDY We examined a single center, retrospective cohort between 2004 and 2007 to determin...

Introduction: Histological analyses of post-transplant liver biopsies may be difficult in distinguishing recurrent chronic hepatitis C (CHC) from other causes of graft dysfunction, especially acute cellular rejection (ACR). Objective: The aim of this study was to compare the histological characteristics of liver biopsies with CHC in transplant and non-transplant patients with hepatitis C virus ...

PurposeUnlike Fontan-associated liver disease, the impact of heart transplant (HT) on Fontan associated kidney disease has not been well described. In this single center study, we sought to characterize natural history chronic in a small cohort patients from listing follow up after HT.MethodsWe conducted retrospective review pediatric at our institution with prior palliation that underwent HT b...

PURPOSE To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors. METHODS Medical records of initial 50 liver transplantations were reviewed retrospectively. RESULTS Twenty-nine patients underwent deceased donor liver transplantation (DDLT)...

BACKGROUND The long-term risk of thrombotic and vascular complications is elevated in liver transplant recipients compared to the general population. Patients with cirrhosis are in a hypercoagulable status during and directly after orthotopic liver transplantation, but it is unclear whether this hypercoagulability persists over time. AIM We aimed to investigate the hemostatic status of liver ...

BACKGROUND Liver transplantation can prolong survival in patients with end-stage liver disease. We have proposed that the Sequential Organ Failure Assessment (SOFA) score calculated on post-transplant day 7 has a great discriminative power for predicting 1-year mortality after liver transplantation. The Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA) score, a modified SOFA...