BACKGROUND Fibrolamellar hepatocellular carcinoma (FLC) is a rare malignancy occurring in young patients without cirrhosis. Objectives of our study were to analyze contrast material uptake in hepatobiliary phase imaging (HBP) in gadoxetic acid-enhanced liver MRI in patients with FLC and to characterize imaging features in sequence techniques other than HBP. METHODS In this retrospective study...

PURPOSE Colorectal cancer is one of the most common forms of cancer, and the development of novel tools for detection and efficient treatment of metastases is needed. One promising approach is the use of radiolabeled antibodies for positron emission tomography (PET) imaging and radioimmunotherapy. Since carcinoembryonic antigen (CEA) is an important target in colorectal cancer, the CEA-specific...

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder in which pathological Langerhans cells accumulate in a variety of organs. LCH usually affects the bone, skin and lymph nodes of children; however, LCH occasionally affects vital organs, including the liver, spleen and pituitary gland. The present study reports a case of an adult LCH patient with marked liver damage, splenomega...

A fully automated method for liver segmentation in contrast enhanced abdominal MRI scans is presented. Liver shape and volume are obtained utilizing a context based approach. Compared to manual segmentation, the obtained liver volumes differ less than 10%. The mean sensitivity of 0.92 is comparable to other published liver segmentation methods.

Objectives We aim to explore and analyze the related influencing factors of liver cardiac iron overload in MDS patients detected by magnetic resonance imaging (MRI).Methods have T2* MRI 105 patients. Among them, 20 accepted examination before after chelation therapy (ICT). Results: found that adjusted ferritin (ASF) was significantly correlated with T2*. RBC transfusion volume, brain natriureti...

BACKGROUND The newly developed magnetic-resonance-imaging (MRI) hepatocyte-specific contrast agent, gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA), has different excretion pathways from the conventional MRI contrast agent, gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). In this study, we compare the enhancement effect of the liver and renal parenchyma betwee...

BACKGROUND European liver fluke Opisthorchis felineus, causing opisthorchiasis disease, is widespread in Russia, Ukraine, Kazakhstan and sporadically detected in the EU countries. O. felineus infection leads to hepatobiliary pathological changes, cholangitis, fibrosis and, in severe cases, malignant transformation of bile ducts. Due to absence of specific symptoms, the infection is frequently n...

Summary A patient diagnosed with late-presenting HIV infection [CD4 count 86 cells/mm 3 , viral load (VL) 95 000 copies RNA/mL], treated DRV/c 800/150 mg (Rezolsta®) and TDF/FTC 200/245 mg, was hospitalized ischemic brain stroke, confirmed by CT scan MRI. Motor functions quickly recovered, but nausea, abdominal heaviness, ascites, hepatosplenomegaly appeared. Laboratory investigations revealed ...

The aim of the present study was to determine the correlation between dual-energy computed tomography (DECT) Hounsfield units (HU) and iron concentration, as well as the correlation between HU and magnetic resonance imaging (MRI)-derived R2* values, in phantoms of the heart and liver tissue. Phantoms were constructed containing pig heart or liver tissue and varying concentrations of iron (0.1, ...

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and liver transplantation is the optimal treatment for selected patients with HCC and chronic liver disease (CLD). Accurate selection of patients for transplantation is essential to maximize patient outcomes and ensure optimized allocation of donor organs. Magnetic resonance imaging (MRI) is a powerful tool for the dete...