Effects of magnetic hydroethanolic extract Nigella sativa and magnesium oxide nanoparticles (MgO) on catalase gene expression in liver diabetic male rats

BACKGROUND Hepatitis is a liver inflammation caused by different agents and remains a public health problem worldwide. Medicinal plants are an important source of new molecules being considered for treatment of this disease. Our work aims at evaluating the hepatoprotective properties of Neoboutonia velutina, a Cameroonian medicinal plant. METHODS The aqueous extract has been prepared using ph...

The antioxidant and hepatoprotective activities of ethyl acetate extract was carefully investigated by the methods of DPPH radical scavenging activity, Hydroxyl radical scavenging activity, Superoxide radical scavenging activity, Hydrogen peroxide radical scavenging activity and its Reducing power ability. All these in vitro antioxidant activities were concentration dependent which were compare...

BACKGROUND/OBJECTIVES Perilla frutescens (L.) Britton var. (PF) sprout is a plant of the labiate family. We have previously reported the protective effects of PF sprout extract on cytokine-induced β-cell damage. However, the mechanism of action of the PF sprout extract in type 2 diabetes (T2DM) has not been investigated. The present study was designed to study the effects of PF sprout extract a...

background & aim:cadmium is an important industrial and environmental pollutant. cadmium is one of the most toxic and carcinogenic heavy metals to organisms. this heavy metal mainly distributes to the liver and kidney in humans and animal and, causing acute hepatic injury. experimental: the ethanol extract of satureja hortensis l. (lamiaceae family), was evaluated for its activity against c...

This study investigates the effect of the methanolic extract of Acalypha wilkesiana on the oxidative stress caused by Plasmodium berghei infection and on the liver of parasitized animals. Phytochemical screening of the extract reveals that it is rich in flavonoids, carotenoids and sterols. Our results showed that liver Malondialdehyde (MDA) significantly (p<0.05) increased while Superoxide Dism...

background salep is used for various purposes in food industries and traditional medicine. therefore, evaluation of its effect on the liver seems to be necessary. objectives the aim of this study was to assess salep effect on liver. materials and methods in this experimental study, various concentrations of salep were intraperitoneally administered to five groups of wistar rats (control, placeb...

Introduction: Hydatid cyst disease is caused by the protoscolices of Echinococcus granulosus. Alkaline phosphatase (ALP) enzyme is required for metabolism, physiology, immunology, and nutrients absorption in parasite. The aim of this study was to compare the level of ALP activity (as a pathological biomarker) in hydatid cyst protoscolices (HCP) with that of sheep liver tissue and to determine t...

Protective effect of ethanolic extract of polyherbalformulation (PHF) of three medicinalplants was studied on carbon tetrachloride induced liver damage in rats. Treatment with 250mg I kg b.w. of ethanolic extract of PHF protected rats against carbon tetrachloride liver injury by significantly lowering 5'NT, GGF, GDH and SDH and bilirubin levels compared to control group of rats. Normalising the...

The present research work was designed to establish the possible preventive and curative hepatoprotective efficacy on CCl4 poisoned rat liver toxicity. Fresh mature seeds were shade dried at room temperature, coarse powdered and extracted with 70% hydroalcohol by Soxhlet’s extraction method. Thereafter, the extract was concentrated using rotary flash evaporator to obtain semisolid crude extract...