background: the pathogenesis of ethanol in the liver and kidney is associated with an increase in free radicals and oxidative stress that leads to structural and functional abnormalities in these vital organs. methods: forty-eight male wistar rats were placed in eight groups and were treated as follows: control group (normal saline), group of ethanol (4 g/ kg), three doses of ardeh and honey co...

background and objectives: nasturtium officinale w.t.aiton (brassicaceae) is used as an edible vegetable in various parts of iran. the aim of the present study was to investigate the protective activity of the methanolic extract of nasturtium officinale against gamma-radiation-induced hepatotoxicity in terms of histopathological changes. methods: male c57 mice were divided into 10 groups. group...

background non-alcoholic fatty liver disease (nafld) is a growing diagnosed condition which causes a wide spectrum of liver disorders. there is a lot of evidence introducing nafld as a risk factor for coronary artery disease (cad) but there is substantial challenge on the independency of this correlation. conclusions according to the results of the current study, the prevalence of nafld among t...

objectives: liver is one of the most sensitive tissues to oxidant damage. hence, the present study was conducted to compare the effects of melissa officinalis (mo) extract and atorvastatin on the activity of liver enzymes in rats. materials and methods: in this experimental study, 60 male wistar rats were selected and allocated to six groups (n=10). the control group received a normal diet, sha...

mammea africana sabine (guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. the hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, to...

objective: lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. zingiber officinale roscoe (ginger) possesses antioxidant properties. in present research, the effect ofhydroalcoholic extract of ginger (heg) on the liver of lamotrigine-treated epileptic rats was investigated material and methods: forty-eight female w...

background: liver transplantation (lt) is now performed as a cure of numerous untreatable pediatric liver diseases. quality of life (qol) can be affected in pediatric patients with lt. many factors are responsible for lower scores of qol. this article aims to detail qol in liver recipients 6 months after lt in children. methods: qol assessed using child health quality-parent form 50 for parents...

a young man presented with a large liver mass and positive hepatitis b virus markers. this 18-year-old male has developed ascites, jaundice, high serum alpha fetoprotein (afp) level, liver mass and portal hypertension, without fever or calcification in the mass. all favored the diagnosis of rapidly, progressive hepatocellular carcinoma, however proven hepatoblastoma in liver biopsy. hepatoblast...

background nonalcoholic steatohepatitis (nash) is a common liver disease that can progress to cirrhosis or hepatocellular carcinoma. it is estimated that up to 3% of the iranian population have this condition. although the pathogenesis of nash is incompletely understood, there is significant evidence pointing to the importance of insulin resistance. metformin is an oral hypoglycemic agent known...