twenty carcasses from a small flock of 5000 four-weeks old broiler chickens were submitted to a poultry disease diagnostic clinic in tehran. at necropsy, 19 carcasses showed the typical lesions of colibacillosis such as pericarditis, prihepatitis and airsaculitis. one case did not show any gross lesion of colibacillosis or chronic respiratory disease (crd) but the liver had an abnormal size con...

objective(s): 3,4-methylenedioxymethamphetamine (mdma) is one of the most popular drugs of abuse in the world with hallucinogenic properties that has been shown to induce apoptosis in  liver cells. the present study aimed to investigate the effects of pentoxifylline (ptx) on liver damage induced by acute administration of mdma in wistar rat. materials and methods: animals were administered with...

hepatitis b, a common infectious disease of liver, is transmitted by blood and body fluids like semen and vaginal fluid that carry hepatitis b virus (hbv).  in chronic infection, medical care is required to decrease possibility of cirrhosis and liver cancer. in the present report, the hepatoprotective effect of an echinacea purpurea preparation (echiherb®) has been described in a patient who su...

A significant decrease of hepatic high-Km glucose- phosphorylating enzyme glucokinase (ATP- D- glucose 6- phosphotransferase, EC 2.7. 1.2, GK) and low-Km hexokinases (EC 2.7. 1.1. HK) activities were noticed in liver treated with 2, 2'- dichlorodiethyl sulfide (sulfur mustard, HD) when injectedinteraperitoneally to male rats in 114 LD50. This decrease occurred 1.5 to 5.5 hours after the in...

The liver is the only organ that can regenerate and regain its original tissue-to-body weight ratio within a short period of time after tissue loss. Insufficient regeneration in patients partial hepatectomy or transplantation with grafts often leads to post-hepatectomy failure small-for-size syndrome, respectively. Enhancing injury might improve outcomes increase patient survival. Liver compris...

Gamma radiation produces free radicals when interacting with cells. The radical can be neutralized and caught by an antioxidant compound. This research aimed to analyze the effect of gamma exposure treated Curcuma xanthorrhiza extract capsules on cells damage mice’s liver. study used mice Balb/c strain average body weight 18-20 grams, aged 6-8 weeks male. required 80 animals for 3 groups, namel...

Background: Fasciolosis is a crucial helminthes disease caused by two trematodes of the genus Fasciola: Fasciola hepatica (temperate liver fluke) and gigantica (tropical fluke). Methods: A cross-sectional study was conducted on cattle sheep in slaughterhouse to detect animals infected with Fasciolosis. Liver samples were collected from transferred laboratory for histopathological immunohistoche...

background: stem-cell technology has been advocated as a potentially curative option for treatment of both type 1 and type 2 diabetes. in the current study, we aimed to assess the effectiveness of allotransplantation of fetal liver-derived cells for treatment of patients with type 1 diabetes. methods: for the purpose of the current study, 72 patients with recently diagnosed type 1 dm were recru...

The hepatitis A virus (HAV) induces severe acute liver injury and is adapted to human monkey cell lines but not other cells. In this study, the HAV was inoculated into porcine kidney (PK-15) cells determine its infectivity in growth pattern of PK-15 compared with fetal rhesus (FRhK-4) less efficient conclusion, replication verified for first time. Further investigations will be needed identify ...

objective(s):  protective effects of different extracts and essential oil from pimpinella anisum           l. seeds were examined against carbon tetrachloride (ccl4)-induced toxicity. the parameters such as serum transaminases, lactate dehydrogenase activity, hepatic glutathione content, liver lipid peroxidation and histopathological changes of liver were assessed as toxicity markers. in the in...