BACKGROUND Lithium has been the gold standard in treating bipolar disorder. In recent years, the use of lithium seems to be diminished although it is well tolerated among the bipolar disorder patients. SUBJECTS AND METHODS This study aimed to evaluate the efficacy and tolerability of lithium as well as to determine factors associated with lithium response among patient with bipolar disorder. ...

in the present study, interactive effects of d1 and d2 dopamine receptors antagonists and different periods of lithium pretreatment on morphine dependence in mice have been investigated. this study was designed to investigate whether the hypothesis that lithium and dopaminergic mechanisms via their effects on phosphoinositide pathways and calcium flux could influence morphine withdrawal respons...

The aim of this study was to evaluate the effects of hydrofluoric acid (HF) concentration and previous heat treatment (PHT) on the surface morphology and micro-shear bond strength (mSBS) of a lithium disilicate glass ceramic (EMX) to resin cement. One hundred four EMX specimens were randomly assigned to two groups (n=52) according to the HF concentration: 5% and 10%. A new random distribution w...

it has been reported that cither lithium or verapamil can potentiate the neuromuscular blocking activity of certain neuromuscular blockers. in the present investigation, possible interaction of verapamil with lithium has been described. the dose ■ response effects of verapamil and lithium on diaphragmatic contractility were assessed in vitro. mechanical responses of the muscle to indirect (nerv...

objective: the purpose of this study was to evaluate the effect of adjunctive topiramate in treating acute mania. methods: in this study which was a double-blinded randomized clinical trial, 46 bipolar patients in manic episode, were treated with lithium carbonate and topiramate versus lithium carbonate and placebo and treatment responses were assessed by young mania rating scale (ymrs) weekly....

Spinel-type of MnO2 nanoparticles which successfully synthesized by a hydrothermal process, have a required capacity for lithium uptake from liquid resources. Themost lithium adsorption capacity of 6.6 mmol/g of up to now was found to be an important limiting parameter for industrial applications. Therefore, increasing uptake capacity of these ion sieve...

Considering the physiological role of epiphysis in functional activity and defense reactions of the body, this study was carried out to evaluate changes of lithium level due to biorhythms of epiphysis. For this purpose, albino mice (6-month old) were used. The animals were kept in light (resulting in inhibition of the activity of epiphysis) and dark (which increases the activity of epiphysis) e...

In the present study, the interactions of three different lithium species Li+, Li3+ and CH3Li with several different sites of the most stable tautomers of DNA nucleo-bases are presented. This investigation is based on the results of thermochemical properties, Quantum Theory of Atoms in Molecules (QTAIM) and Natural Bond Orbi...