نتایج جستجو برای: lisinopril dehydrate

تعداد نتایج: 1360  

2013
Gary G. Tse Alberto S. Santos-Ocampo Dominic C. Chow Aaron M. McMurtray Beau K. Nakamoto

Parkinsonism in SLE is rare. Diffuse leukoencephalopathy is equally uncommon and is associated with a poor prognosis. We present a single case of a 50-year-old Filipino man who presented with a generalized discoid rash after starting lisinopril. The rash persisted despite discontinuation of lisinopril, and over the next three months, he developed rapidly progressive parkinsonism. Brain MRI show...

Journal: :Pharmacotherapy 1993
V Bhatt-Mehta K S Deluga

The use of angiotensin-converting enzyme (ACE) inhibitors in pregnancy has been associated with neonatal morbidity and mortality. The mechanism of renal dysfunction likely is related to fetal hypotension and prolonged decreased glomerular filtration. Six of 14 previously published cases of neonatal renal failure after maternal ACE inhibitor therapy resulted in death. Eight infants survived afte...

2016
Doris E. Braun Ulrich J. Griesser

The complex interplay of temperature and water activity (aw) / relative humidity (RH) on the solid form stability and transformation pathways of three hydrates (HyA, HyB and HyC), an isostructural dehydrate (HyAdehy ), an anhydrate (AH) and amorphous brucine has been elucidated and the transformation enthalpies quantified. The dihydrate (HyA) shows a non-stoichimetric (de)hydration behavior at ...

2013
D. L. Farrugia C. M. Shoemake E. Attard L. M. Azzopardi S. J. Mifsud

Crataegus monogyna is mainly used in the treatment of cardiac and circulatory system disorders. In vitro and clinical studies are indicative of the fact that the hydroethanolic extract of C. monogyna has angiotensin converting enzyme (ACE) inhibitory activity. This study sought to support these claims through the use of in silico modelling techniques. Possible binding conformations for β-amyrin...

2013
Najma Sultana M. Saeed Arayne Rubina Siddiqui Safila Naveed

High performance liquid chromatographic method was developed valdated and applied for the simultaneous determination of lisinopril and NSAIDs in bulk, pharmaceuticals formulations and human serum. A Purospher star C18 (5 μm, 25 × 0.46 cm) column was used with mobile phase consisting of methanol: water: acetonitrile (80:17.5:2.5 v/v, pH 3.0) and quantitative evaluation was performed at 225 nm wi...

Journal: :Biochemical and biophysical research communications 2003
Jorge H Fernandez Mirian A F Hayashi Antonio C M Camargo Goran Neshich

Angiotensin I-converting enzyme (ACE) is a dipeptidyl carboxypeptidase which converts angiotensin I into the vasopressor peptide angiotensin II and also inactivates the hypotensive peptide bradykinin, playing an important role in blood pressure regulation. The present work describes the molecular modeling of the N-terminal human somatic ACE in complex with the inhibitor lisinopril, identifying ...

Journal: :Journal of the American Chemical Society 2009
Sofya Kostina Berezin Jeffery T Davis

We report that an amphiphilic bis-catechol (3) functions as a transmembrane anion transporter. Activity depends on the catechol's substitution and amphiphilicity. We also describe a liposomal assay that allows one to readily measure anion transport selectivity. This assay reveals that anion transport selectivity for this amphiphilic bis-catechol follows a Hofmeister sequence wherein anions that...

Journal: :Journal of Bioequivalence & Bioavailability 2016

Journal: :British Journal of Clinical Pharmacology 1989

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