نتایج جستجو برای: like growth factor receptor

تعداد نتایج: 2394610  

Journal: :Pharmacological research 2015
Francisco Westermeier Mario Bustamante Mario Pavez Lorena García Mario Chiong María Paz Ocaranza Sergio Lavandero

Insulin-like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) have been proposed to be important mediators in cardioprotection. A large body of evidence indicates that insulin like growth factor-1 has pleotropic actions in the heart (i.e., contractility, metabolism, hypertrophy, autophagy, senescence and cell death) and, conversely, its deficiency is associated with impaired cardiac fun...

2010
Amanda L. Kauffman Jasmine M. Ashraf M. Ryan Corces-Zimmerman Jessica N. Landis Coleen T. Murphy

Of all the age-related declines, memory loss is one of the most devastating. While conditions that increase longevity have been identified, the effects of these longevity-promoting factors on learning and memory are unknown. Here we show that the C. elegans Insulin/IGF-1 receptor mutant daf-2 improves memory performance early in adulthood and maintains learning ability better with age but, surp...

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