Glycyrrhiza glabra (licorice), is used for therapeutic purposes since ages. Neuropathic pain a disease with complex pathophysiology, involving dysfunction in multiple ion channel receptors such as sodium, transient receptor potential channels, neurotransmitters, inflammatory mediators and reactive oxygen species. Network pharmacology newly emerging approach dealing understanding mechanism of ac...

Herbs have been used as a form of traditional medicine since ancient times. Licorice is one the herbs that has long medicine. This plant contains different compounds, such glycyrrhizin, 18??glycyrrhetinic acid, glabrins A and B, isoflavones, showing various pharmacological activities. Pharmacological experiments shown extracts pure compounds this species exhibit broad biological properties, inc...

Land salinization is widespread in countries of the arid zone, including Aral Sea basin, where 4 million hectares irrigated land are salt-affected, causing high economic losses. Current saline soil reclamation practices include leaching and deep drainage to remove excess water outside zone. Growing pressure on limited resources makes this practice ineffective. An alternative biological methods ...

We describe a patient presenting with hypertension and hypokalaemia who was ultimately diagnosed with liquorice- induced pseudohyperaldosteronism. This rare cause of secondary hypertension illustrates the importance of a methodical approach to the assessment of hypertension.

Mineralocorticoid Receptors (MR) preferentially bind cortisol. A mineralocorticoid effect of cortisol is avoided in some tissues by expression of 11-Beta Hydroxysteroid Dehydrogenase type 2 (11 BHSD2), the enzyme responsible for transformation of cortisol to its 11-keto derivative (cortisone), which has minimal affinity for MR receptors. Only when cortisol is converted to the inactive cortisone...

Amaç: Alternatif tıp, insanlık tarihinde birçok hastalıkla mücadelede önemli bir yere sahiptir. Bu çalışmada Glycyrrhiza glabra L.'nin biyolojik aktivitesi araştırıldı. Gereç ve Yöntem: Bitkinin kök kısımları etanol ile ekstrakte edildi. Antioksidan oksidan potansiyelleri Rel Assay kitleri kullanılarak belirlendi. Antimikrobiyal aktivite, agar seyreltme yöntemi standart bakteri mantar suşlarına...