Lactoferrin (LF) is a multifunctional glycoprotein present in milk. A clinical study showed that enteric-coated bovine LF tablets decrease visceral fat accumulation. Furthermore, animal studies revealed that ingested LF is partially delivered to mesenteric fat, and in vitro studies showed that LF promotes lipolysis in mature adipocytes. The aim of the present study was to determine the mechanis...

Although the immunohistochemical presence of lactoferrin (LF) in pathological neoplastic bone and cartilage samples has previously been studied, no data concerning the distribution of LF in bone metastases of cancers that have originated from different organs are available at present. Consequently, using a monoclonal antibody, we have investigated the immunohistochemical LF pattern in 50 formal...

Study Design A retrospective radiological study of the ligamentum flavum (LF). Purpose We determined the relationship of dorsal spinal LF thickening with age and sex using magnetic resonance imaging (MRI). We also determined whether LF thickening has a predominant tendency to occur at a specific dorsal level and on a specific side. Overview of Literature Many researchers have studied LF thi...

Although a morphologically distinct population of lipid-laden interstitial cells (lipofibroblasts, LF), has been identified, the origins and functions of this population during lung development and disease remain undefined. Illumination of the developmental and functional characteristics of two other populations of lipid-laden mesenchymal cells, namely adipocytes and hepatic lipocytes, has fash...

Systemic anthrax manifests as toxemia, rapidly disseminating septicemia, immune collapse, and death. Virulence factors include the anti-phagocytic gamma-linked poly-d-glutamic acid (PGA) capsule and two binary toxins, complexes of protective antigen (PA) with lethal factor (LF) and edema factor. We report the characterization of LF, PA, and PGA levels during the course of inhalation anthrax in ...

In obesity-related hypertension, activation of the renin-angiotensin system (RAS) has been reported despite marked fluid volume expansion. Adipose tissue expresses components of the RAS and is markedly expanded in obesity. This study evaluated changes in components of the adipose and systemic RAS in diet-induced obese hypertensive rats. RAS was quantified in adipose tissue and compared with pri...

The dependently-typed lambda calculus (LF) supports use of meta-level binding in reasoning about bindings and hypotheticals in programming languages. That is, lambda expressions in LF can be used to model binders and hypothetical judgments depending on fixed-size contexts. However, because LF does not have a concept of variable-arity functions, a hypothetical judgment depending on a variable-si...

The aim of this study was to evaluate the effects of lactoferrin (LF) on the growth of fibroblasts derived from nasal polyps. We showed that the proliferation of fibroblasts was inhibited in a dose-dependent manner by both native and recombinant LF. The greatest inhibition of proliferation was caused by human milk-derived, iron-saturated LF. The inhibition of fibroblast proliferation was not sp...

We assessed the potential of lactoferrin (LF), a multifunctional milk protein, for treatment of oral candidiasis with immunosuppressed mice, which have local symptoms characteristic of oral thrush. Oral administration of bovine LF in drinking water starting 1 day before the infection significantly reduced the number of Candida albicans in the oral cavity and the score of lesions on the tongue o...

w: LF (nu) 67-9 (11 1)* 53-2 (7 3) HF (nu) 32-1 (8 1)* 42-7 (4 9) LF/HF 2-33 (0 88)* 1-28 (0-21) Stage 2 non-REM sleep: LF (nu) 39-9 (13-9) 36-2 (15-5) HF (nu) 60-1 (15-2) 57.3 (11-2) LF/HF 0-84 (0 63) 0-76 (0 48) Stage 3-4 non-REM sleep: LF (nu) 26-9 (11 1) 25-9 (8-6) HF (nu) 73-1 (14 6) 66-2 (11-6) LF/HF 0 47 (0 41) 0-46 (0-32) REM sleep: LF (nu) 56-3 (12 8) 53 2 (16-6) HF (nu) 43 7 (8 3) 41 ...