نتایج جستجو برای: lewy cfl criteria

تعداد نتایج: 277021  

Journal: :Brain : a journal of neurology 2010
Katrin Beyer Montserrat Domingo-Sàbat Cristina Santos Eduardo Tolosa Isidro Ferrer Aurelio Ariza

Lewy body diseases include dementia with Lewy bodies and Parkinson's disease. Whereas dementia with Lewy bodies and Parkinson's disease can be distinguished as separate clinical entities, the pathological picture is very often identical. α-synuclein aggregation is a key event in the pathogenesis of Lewy body diseases and β-synuclein inhibits α-synuclein aggregation in vitro and in vivo. Recentl...

2016
MK Morris DC Clarke LC Osimiri DA Lauffenburger

A major challenge in developing anticancer therapies is determining the efficacies of drugs and their combinations in physiologically relevant microenvironments. We describe here our application of "constrained fuzzy logic" (CFL) ensemble modeling of the intracellular signaling network for predicting inhibitor treatments that reduce the phospho-levels of key transcription factors downstream of ...

2013
Elmano Pinto

The cell-free layer (CFL) is a hemodynamic phenomenon that has an important contribution to the rheological properties of blood flowing in microvessels. The present work aims to find the closest function describing RBCs flowing around the cell depleted layer in a polydimethysiloxane (PDMS) microchannel with a diverging and a converging bifurcation. The flow behavior of the CFL was investigated ...

2016
Krzysztof Chalupka Frederick Eberhardt Pietro Perona

Causal feature learning (CFL) (Chalupka et al., Proceedings of the Thirty-First Conference on Uncertainty in Artificial Intelligence. AUAI Press, Edinburgh, pp 181–190, 2015) is a causal inference framework rooted in the language of causal graphical models (Pearl J, Reasoning and inference. Cambridge University Press, Cambridge, 2009; Spirtes et al., Causation, Prediction, and Search. Massachus...

2006
Stefan B. Rüster Igor A. Shovkovy Dirk H. Rischke

We study the phase diagram of dense, locally neutral three-flavor quark matter as a function of the strange quark mass, the quark chemical potential, and the temperature, employing a general nine-parameter ansatz for the gap matrix. At zero temperature and small values of the strange quark mass, the ground state of matter corresponds to the color-flavor-locked (CFL) phase. At some critical valu...

2005
Sanatan Digal Tetsuo Hatsuda Munehisa Ohtani

We study thermal phase transitions of color superconductivity by the lattice simulations of the Ginzburg-Landau (GL) effective theory. The theory is equivalent to the SUf(3) × SUc(3) Higgs model coupled to SUc(3) color gauge fields. From the eigenvalues of a 3×3 gauge-invariant diquark composite, a clear distinction between the 2-flavor color superconductivity (2SC) and the color flavor locking...

2004
CRISTINA MANUEL

Transport coefficients of dense quark matter are needed to study properties of compact stars. They can tell us about the cooling, vibrational and rotational properties of the star. We report below a computation of the shear viscosity in the CFL phase at low temperature T . CFL quark matter behaves as a superfluid, and at low T its transport properties are dominated by the collisions of superflu...

Journal: :Archives of neurology 2000
H A Crystal D Dickson P Davies D Masur E Grober R B Lipton

CONTEXT With the recent change in pathological criteria for Alzheimer disease (AD), a group of patients has emerged who do not meet pathological criteria for any well-characterized degenerative dementias. Whether these unclassified patients have vascular dementia or some other form of dementia is not known. OBJECTIVE To determine the clinical characteristics, pathological substrate, and relat...

2015
L. A. Sternberger

Three patients with clinical Alzheimer's disease were found at postmortem examination to have Lewy-bodies and Lewy-like bodies in the cerebral cortex and the pigmented brainstem nuclei. Neuritic plaques were found in neocortical areas but no neurofibrillary tangles. The distribution of cortical neuronal inclusions correlated with the proposed projection of dopamine terminals. Neuronal cell loss...

Journal: :Annals of internal medicine 2013
Nasseer Masoodi

Review scope Included studies compared ChEIs (donepezil, rivastigmine, galantamine, or tacrine) with placebo for ≥ 1 month in adults with mild cognitive impairment (as defined by each study but including subjective memory complaint and relatively preserved daily functioning). Primary outcomes were progression to dementia, which included Alzheimer disease (National Institute of Neurological and ...

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