OBJECTIVE This study tests the usefulness of ceftriaxone combined with ampicillin as an alternative to ampicillin plus gentamicin for the treatment of experimental endocarditis due to Enterococcus faecalis without high-level resistance to aminoglycosides. It also determines whether adding ceftriaxone to ampicillin and gentamicin increases the effectiveness against experimental enterococcal endo...

Resistant enterococci is a real threat and continuous surveillance is necessary to monitor its magnitude. Risk factors and phenotypic characteristics of VRE isolated in Gandhi memorial and associated hospital, K.G’s .Medical University Lucknow a tertiary care setup. Method: Enterococci were isolated from various clinical specimens and identified phenotypically, vancomycin resistance pattern usi...

Introduction: Escherichia coli (E.coli) as a main cause of both nosocomial and community-acquired infections in humans have a relative potential to develop resistance. Nowadays, most infections caused by ESBL-producing E.coli (ESBLEC) had mostly been described as nosocomial acquired or nursing home related. In this study, we employed E-test assay to detect antibiotic resistance of E.coli ...

Present study investigated the antibiotic resistance profile of bacterial strains isolated from soil, sediment and waters of Eloor-Edayar Industrial belt of Kerala, South India. A total of 165 bacterial strains were isolated and tested for their sensitivity to 11 common antibiotics (Ampicillin, Erythromycin, Gentamycin, Nalidixic acid, Penicillin, Vancomycin, Novobiocin, Amikacin, Kanamycin, St...

The aim of this study was to investigate the role of inducible nitric oxide synthase (iNOS) in gentamicin-induced acute tubular necrosis in rats using the iNOS inhibitor L-N6-(1-iminoethyl) lysine (L-NIL). Wistar rats, both sexes (n=18), were equally divided into three groups. Gentamicin group received intraperitoneally (i.p.) gentamicin in 0.9 % NaCl at a dose of 80 mg/kg/day for five consecut...

BACKGROUND Wound infections have been a problem in the field of surgery for a long time. Advances in control of infections have not completely eradicated this problem because of development of drug resistance. Antimicrobial resistance can increase complications and costs associated with procedures and treatment. OBJECTIVE A study was carried out on drug sensitivity patterns of bacterial isola...

OBJECTIVES Bartonella bacilliformis is the aetiological agent of Carrion's disease. Although ciprofloxacin, rifampicin and erythromycin have been successfully used in the treatment of the disease, failures and relapses have been reported. The objective of our study was to select in vitro mutants resistant to antibiotics in order to determine the frequency of mutations and to characterize the me...

The intestinal microbiota, a barrier to the establishment of pathogenic bacteria, is also an important reservoir of opportunistic pathogens. It plays a key role in the process of resistance-genes dissemination, commonly carried by specialized genetic elements, like plasmids, phages, and conjugative transposons. We obtained from strains of enterobacteria, isolated from faeces of newborns in a un...