This paper addresses the problem of optimizing a factorial system with multiple responses. A heuristic termed probabilistic sequential methodology (PSM) is proposed. The PSMidenti® es those designs that maximize the likelihood of satisfying a given set of functional requirements. It is based on sequential experimentation, statistical inference and a probabilistic local search. The PSM comprises...

The advent of the Internet/World Wide Web and its application to the field of education has provided new opportunities for teaching and learning. To cater for the large number of potential new students worldwide, many universities and for-profit education providers have introduced online programs. In Singapore, Web-based online education has not attracted as many students as had been expected. ...

Qualitative analyses were carried out on solid medium with insoluble collagen 0.25% (w/v) to detect proteases with collagenolytic activity produced by Bacillus sp. In cultures incubated for 24 h, a 23 full factorial design with four repetitions at the center point was developed to analyze the effects and interactions between initial pH, temperature and the concentration of gelatin. Based on the...

The chemical step in the chemoenzymatic synthesis of bioengineered heparin has been examined and optimized statistically using a response surface methodology. A four factor, two level full factorial design experiment and a three factor Box-Behnken design were carried out. The goal was to establish a method to prepare N-sulfo, N-acetyl heparosan of the desired N-acetyl content, number average mo...

The influence of perceived severity and sense of personal responsibility of police officers on their level of involvement in cases of intimate partner violence against women is analyzed. Three levels of police involvement are considered: low, medium, and high. The sample consists of 143 Spanish police officers. A 2 x 2 x 3 factorial design is conducted to test hypotheses. Effects of perceived s...

The stiffness of articular cartilage increases dramatically with increasing rate of loading, and it has been hypothesized that increasing the stiffness of the subchondral bone may result in damaging stresses being generated in the articular cartilage. Despite the interdependence of these tissues in a joint, little is understood of the effect of such changes in one tissue on stresses generated i...

The purpose of this study is to determine the use audiovisual media that can provide examples in memorizing Qur'an terms writing (visual) and pronunciation (audio) so learning process will be more meaningful affect student outcomes. This research was conducted at Integrated Islamic Private Junior High School Medan. Quasi Experimental type with factorial design (factorial experimental design). r...