BACKGROUND Although leptospirosis is a reemerging zoonosis of global importance, outbreaks related to agricultural exposures are primarily situated in tropical countries. In July 2007, a suspected leptospirosis outbreak was recognized among strawberry harvesters from Eastern Europe who were working in Germany. An investigation was initiated to identify the outbreak source and the risk factors f...

Leptospirosis is a zoonotic disease with global distribution that caused by pathogenic spirochetes of the genus Leptospira. Accurate diagnosis for differentiation of leptospirosis from other pyrogenic infections prevailing in the same locality and is imperative for proper treatment. Therefore a molecular diagnostic test with high specificity and sensitivity such as PCR is essential. Gene encodi...

The prognosis of leptospirosis depends of severity, early diagnosis and prompt intensive treatment. Only few studies estimate the costs in outbreak of leptospirosis. We aimed to assess the cost effectiveness of predicting severity in leptospirosis by retrospective cohort study of 100 consecutive hospitalized patients with leptospirosis (1976-2015). The prices of service, investigations, drugs a...

Leptospirosis, a worldwide distributed zoononis caused by bacteria of the genus Leptospira (antigenically classified into serovars), may be direct or indirectly transmitted through infected urine or environment. Several domestic and wild animals are leptospirosis reservoirs. The disease presents occupational character since it is widely reported in professionals that work in humid environments ...

Leptospirosis is one of the common re-emerging zoonotic diseases transmitted from infected animals to humans. It is a bacterial infection caused by a species of pathogenic leptospiragenus called Spirochaetes. The very first case of human leptospirosis in Malaysia was discovered by Fletcher in the year 1925. Pathogenic leptospires can spread through the urine of carrier animals to the environmen...

The authors evaluated a simple latex agglutination test for the serodiagnosis of acute human leptospirosis. A total of 380 serum samples from 85 confirmed leptospirosis patients and 202 non-leptospirosis patients were selected Using the selected cut-off value of weakly positive, the overall sensitivity and overall specificity of the test were 94.1% and 97.0% respectively. The weighted kappa val...

Persistent symptomless human metapneu-movirus infection in hematopoietic stem cell transplant recipients. metapneumovirus infection in lung transplant recipients: clinical presentation and epidemiology. Characterization of multidrug-resistant in-fl uenza A/H3N2 viruses shed during one year by an immunocompromised child. et al. Virological features and clinical manifestations associated with hum...

The history and epidemiology of human leptospirosis in Malaysia from 1925 to 2012 are described. Previous studies have demonstrated that leptospirosis is an endemic disease in Malaysia occurring in both urban and rural locations. The number of cases has risen dramatically since the Ministry of Health Malaysia highlighted leptospirosis as a notifiable disease in 2010, with reported cases increas...

Leptospirosis is a zoonotic disease that causes severe manifestations such as Weil's disease and pulmonary hemorrhage syndrome. The aim of this study was to evaluate whether reactive oxygen species (ROS) production and antioxidant reduced glutathione (GSH) levels are related to complications in patients hospitalized with leptospirosis. The ROS production and GSH levels were measured in blood sa...