The anginal threshold was determined by atrial pacing in 23 patients with coronary artery disease. Twelve of the 23 subjects also performed supine exercise at progressive workloads until the onset of angina. Atrial pacing produced a fall in left ventricular stroke work index and left ventricular end-diastolic pressure (LVEDP); cardiac output increased, and, with the onset of angina, left ventri...

Acute and rapidly reversible left ventricular dysfunction may be triggered by various psychological and physical insults. This entity is now well known as stress cardiomyopathy or Takotsubu cardiomyopathy. Suicidal hanging involves intense emotional outburst and the act of hanging is an extreme physical stress. We report a case of rapidly reversible left ventricular dysfunction following attemp...

BACKGROUND AND AIM Rheumatic mitral regurgitation is rather common in developing countries. It usually progresses insidiously, because the heart compensates for increasing regurgitant volume by left-atrial enlargement, causes left-ventricular overload and dysfunction, and yields poor outcome when it becomes severe. Doppler-echocardiographic methods can be used to quantify the severity of mitral...

INTRODUCTION AND OBJECTIVES There is extensive controversy exists on whether cardiac resynchronization therapy corrects electrical or mechanical asynchrony. The aim of this study was to determine if there is a correlation between electrical and mechanical sequences and if myocardial scar has any relevant impact. METHODS Six patients with normal left ventricular function and 12 patients with l...

Background: Takotsubo Cardiomyopathy (TTC) is known as a syndrome of transient and acute left ventricular dysfunction caused by emotional physiological stressors. Due to variety complications in the phase, recently, there has been increased attention TTC

Objectives: To determine whether blood natriuretic peptide concentrations are helpful in identifying or excluding left ventricular systolic dysfunction in stable survivors of acute myocardial infarction. Design: Comparison of blood natriuretic peptide concentrations with echocardiographic assessment of left ventricular systolic function in a general practice population. Setting: Practices in We...

BACKGROUND Elevated B-type natriuretic peptide (BNP) levels are predictive of cardiovascular events in patients on chronic maintenance haemodialysis, even in those without apparent cardiovascular disorders when they start dialysis. In the present study, we tested the hypothesis that left ventricular diastolic dysfunction increases BNP levels and can predict cardiovascular events in patients on ...

Left ventricular performance was determined by echocardiography in 44 black children with homozygous sickle cell anaemia and a control group of 28 normal black children of comparable age. Statistically significant differences were observed between the children with sickle cell anaemia and the normal group in left ventricular ejection fraction (sickle cell anaemia group: 0-59 + 0.01 [mean + stan...