Experiments were carried out to evaluate the toxicity of six botanicals, Bazna (Zanthoxylum rhetsa), Ghora-neem (Melia sempervirens), Hijal (Barringtonia acutangula), Karanja (Pongamia pinnata), Mahogoni (Swietenia mahagoni) and Neem (Azadirachta indica) against red flour beetle, Tribolium castaneum Herbst. Leaf and seed extracts were prepared by using acetone, methanol and water as solvents. T...

Ficus pumila leaf and the seed oil of Moringa oleifera contain significant amount of vitamins and vital nutrients which mitigate vunerable diseases. Essentially, the goal is to screen the stability of rutin, a valuable antioxidant and validate the mechanism of its kinetic degradation in Ficus pumila leaf with and without oil extracted from M. Oleifera seeds. Experiments were planned according t...

INTRODUCTION Debridement and disinfection of the root canal is a crucial step in the success of endodontic treatment. Several antimicrobial agents alone or in combination are used to achieve this. The objective of this in vitro study was to assess the antimicrobial efficacy of neem (Azadirachta indica) extract against Enterococcus faecalis. MATERIALS AND METHODS Neem leaf extract, 2% chlorhex...

Aqueous leaf extract of four different species of Datura viz. D.stramonium L., D. innoxia Mill.Gard, D. metal L. and D. ferox L. Amoen were tested for their antifungal activity against phytopathogenic molds in terms of mycelial growth of Alternaria solani and Fusarium oxysporum f.sp. udum causing early blight of tomato and wilt of pigeonpea respectively. The extract of Datura sp. at 5, 10, 15 a...

The antiviral activity of Callissia fragrans and Simnondsia chinensis aquatic and ethanol leaf extracts, as well as purified fractions from these extracts was studied against herpetic viruses in vitro. Ethanol extract of C. fragrans effectively inhibited the infection of Vero cells by HSV-1, HSV-2 in vitro, while its aquatic extract inhibited only VZV. Although S. chinensis leaf extract strongl...

The study was designed to evaluate the anti-diabetic effect of aqueous extract of Bauhinia tomentosa L. leaf on alloxan induced Wistar albino rats. Diabetes was induced in albino rat models with alloxan monohydrate (150mg/kg body weight). Aqueous leaf extract of Bauhinia tomentosa at the dose of 300 mg/kg was orally administered once a day for 30 days to the diabetic animals. In this study, gly...

to determine the anticonvulsant activity of the leaf extract of croton zambesicus in mice and rats, and in order to verify the traditional use of the plant in the treatment of epilepsy. the pentyleneterazole (ptz) and the maximal electroshock seizure (mes) models were used for assessing the anticonvulsant effects of the aqueous leaf extract in mice and rats. in the ptz test, the leaf extract (1...

BACKGROUND In Ethiopia, the leaves of Syzygium guineense have been found useful for the prevention and cure of malaria, and demonstrated antiplasmodial activity in vitro. Nevertheless, no scientific study has been conducted to confirm its antimalarial activity in vivo. Therefore, the objective of the study was to evaluate the antimalarial effect of Syzygium guineense leaf extract in mice. MET...

The zebrafish is becoming an increasingly popular model system for both automated drug discovery and investigating hypercholesterolemia. Here we combine these aspects and for the first time develop an automated high-content confocal assay for treatments of hypercholesterolemia. We also create two algorithms for automated analysis of cardiodynamic data acquired by high-speed confocal microscopy....